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13-Oxyingenol dodecanoate, a cytotoxic ingenol derivative, induces mitochondrial apoptosis and caspase-dependent Akt decrease in K562 cells.
Liu, Ming; Zhang, Weiyi; Wang, Genzhu; Song, Xiaoping; Zhao, Xingzeng; Wang, Xiangyun; Qi, Xin; Li, Jing.
Afiliação
  • Liu M; Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China.
  • Zhang W; Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China.
  • Wang G; Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China.
  • Song X; Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China.
  • Zhao X; Institute of Botany, Jiangsu Province and Chinese Academy of Sciences (Nanjing Botanical Garden, Mem. Sun Yat-sen), Nanjing, 210014, China.
  • Wang X; Nanjing Spring & Autumn Biological Engineering Co., Ltd, China, Nanjing, 210014, China.
  • Qi X; Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China.
  • Li J; Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China. ljlilac@163.com.
Tumour Biol ; 37(5): 6227-38, 2016 May.
Article em En | MEDLINE | ID: mdl-26615422
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mielogênica Crônica BCR-ABL Positiva / Apoptose / Diterpenos / Proteínas Proto-Oncogênicas c-akt Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mielogênica Crônica BCR-ABL Positiva / Apoptose / Diterpenos / Proteínas Proto-Oncogênicas c-akt Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article