Jerking & confused: Leucine-rich glioma inactivated 1 receptor encephalitis.

Casault, Colin; Alikhani, Katayoun; Pillay, Neelan; Koch, Marcus

Casault, Colin; Alikhani, Katayoun; Pillay, Neelan; Koch, Marcus.

Afiliação

Casault C; Department of Clinical Neurosciences and Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada. Electronic address: ccasault@ucalgary.ca.
Alikhani K; Department of Clinical Neurosciences and Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada.
Pillay N; Department of Clinical Neurosciences and Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada.
Koch M; Department of Clinical Neurosciences and Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada; Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.

J Neuroimmunol ; 289: 84-6, 2015 Dec 15.

Article em En | MEDLINE | ID: mdl-26616875

ABSTRACT

ABSTRACT

This is a case of autoimmune encephalitis with features of faciobrachial dystonic seizures (FBDS) pathognomonic for Leucine Rich Glioma inactivated (LGI)1 antibody encephalitis. This voltage-gated potassium channel complex encephalitis is marked by rapid onset dementia, FBDS and hyponatremia, which is sensitive to management with immunotherapy including steroids, IVIG and other agents. In this case report we review the clinical features, imaging and management of this condition.

Assuntos

Anticorpos/sangue; Encefalite/sangue; Encefalite/imunologia; Proteínas/imunologia; Corticosteroides/uso terapêutico; Idoso; Tonsila do Cerebelo/diagnóstico por imagem; Tonsila do Cerebelo/efeitos dos fármacos; Tonsila do Cerebelo/metabolismo; Transtornos Cognitivos/tratamento farmacológico; Transtornos Cognitivos/etiologia; Encefalite/complicações; Encefalite/terapia; Humanos; Peptídeos e Proteínas de Sinalização Intracelular; Imageamento por Ressonância Magnética; Masculino; Tomografia por Emissão de Pósitrons; Convulsões/tratamento farmacológico; Convulsões/etiologia

Palavras-chave

Faciobrachial dystonic seizures; LGI1 encephalitis; Limbic encephalitis; Paraneoplastic disease; Steroid sensitive encephalopathy

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas / Encefalite / Anticorpos Tipo de estudo: Etiology_studies Limite: Aged / Humans / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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