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Malignant meningitis secondary to oesophageal adenocarcinoma presenting with sensorineural hearing loss: a series of three cases and discussion of the literature.
Adams, Mark; Doherty, Carolynne; O'Kane, Anna; Hall, Samuel; Forbes, Raeburn B; Herron, Brian; McNaboe, Edward J.
Afiliação
  • Adams M; Department of Otolaryngology/Head and Neck Surgery, Craigavon Area Hospital, Portadown, Co Armagh, Northern Ireland, UK. jadams08@qub.ac.uk.
  • Doherty C; Department of Otolaryngology, Royal Victoria Hospital, 274 Grosvenor Road, Belfast, BT12 6BA, Northern Ireland, UK. jadams08@qub.ac.uk.
  • O'Kane A; Department of Neurology, Craigavon Area Hospital, Portadown, Co Armagh, Northern Ireland, UK.
  • Hall S; Department of Neurology, Craigavon Area Hospital, Portadown, Co Armagh, Northern Ireland, UK.
  • Forbes RB; Department of Neurology, Craigavon Area Hospital, Portadown, Co Armagh, Northern Ireland, UK.
  • Herron B; Department of Otolaryngology/Head and Neck Surgery, Craigavon Area Hospital, Portadown, Co Armagh, Northern Ireland, UK.
  • McNaboe EJ; Department of Neuropathology, Royal Victoria Hospital, Belfast, Northern Ireland, UK.
Eur Arch Otorhinolaryngol ; 273(9): 2481-6, 2016 Sep.
Article em En | MEDLINE | ID: mdl-26645106
Malignant meningitis may rarely present to the otolaryngologist. We report our experience with 3 patients presenting with sudden, progressive bilateral sensorineural hearing loss secondary to malignant meningitis. The primary tumour in all 3 cases was oesophageal adenocarcinoma. All 3 cases were notable for the rapidity of the patients' clinical deterioration; the interval from presentation to death ranged from 21 to 28 days. We suggest that otolaryngologists should remain vigilant to the possibility of this devastating diagnosis and have a low threshold for further investigation in patients with suspicious features. It is important to note that initial MRI and lumbar puncture may be negative and repeat testing should be undertaken if there is clinical suspicion.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Esofágicas / Adenocarcinoma / Perda Auditiva Súbita / Carcinomatose Meníngea / Perda Auditiva Neurossensorial Tipo de estudo: Etiology_studies Limite: Adult / Aged / Humans / Male / Middle aged Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Esofágicas / Adenocarcinoma / Perda Auditiva Súbita / Carcinomatose Meníngea / Perda Auditiva Neurossensorial Tipo de estudo: Etiology_studies Limite: Adult / Aged / Humans / Male / Middle aged Idioma: En Ano de publicação: 2016 Tipo de documento: Article