fMRI and Anesthesia.
Int Anesthesiol Clin
; 54(1): 129-42, 2016.
Article
em En
| MEDLINE
| ID: mdl-26655513
ABSTRACT
BOLD activation studies discussed vary in the anesthetic agent studied (propofol, sevoflurane, and isoflurane), the concentration of the anesthetic (mostly under 0.5MAC or equivalent doses), and the activation paradigm/functional activation. The data analysis technique also differs between the studies. Notwithstanding these variations, the results can be summarized as follows Higher order association cortices are more sensitive to anesthesia. Higher order regions processing language and semantics (regions in the frontal cortex) are affected at a lower concentration of anesthetic as compared with regions processing auditory stimuli. Whereas primary visual activation regions in the visual cortex and the thalamus are less sensitive, higher order visual spatial attention regions in the parietal cortex are more sensitive to anesthesia. In most studies, the loss of consciousness (no response to call) is achieved at or below 0.5MAC of anesthesia.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Encéfalo
/
Imageamento por Ressonância Magnética
/
Anestesia
/
Anestésicos
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article