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BACE-1 is expressed in the blood-brain barrier endothelium and is upregulated in a murine model of Alzheimer's disease.
Devraj, Kavi; Poznanovic, Slobodan; Spahn, Christoph; Schwall, Gerhard; Harter, Patrick N; Mittelbronn, Michel; Antoniello, Katia; Paganetti, Paolo; Muhs, Andreas; Heilemann, Mike; Hawkins, Richard A; Schrattenholz, André; Liebner, Stefan.
Afiliação
  • Devraj K; Edinger Institute of Neurology, Goethe University Medical School, Frankfurt, Germany drivak@yahoo.com stefan.liebner@kgu.de.
  • Poznanovic S; Orgentec GmbH, Mainz, Germany.
  • Spahn C; Institute of Physical and Theoretical Chemistry, Goethe-University, Frankfurt, Germany.
  • Schwall G; Orgentec GmbH, Mainz, Germany.
  • Harter PN; Edinger Institute of Neurology, Goethe University Medical School, Frankfurt, Germany.
  • Mittelbronn M; Edinger Institute of Neurology, Goethe University Medical School, Frankfurt, Germany.
  • Antoniello K; AC Immune SA, PSE-B EPFL, Lausanne, Switzerland.
  • Paganetti P; AC Immune SA, PSE-B EPFL, Lausanne, Switzerland.
  • Muhs A; AC Immune SA, PSE-B EPFL, Lausanne, Switzerland.
  • Heilemann M; Institute of Physical and Theoretical Chemistry, Goethe-University, Frankfurt, Germany.
  • Hawkins RA; Dept of Physiology/Biophysics, University of Health Sci./Chicago Medical School, Illinois, USA.
  • Schrattenholz A; Pivot GmbH, Trier, Germany.
  • Liebner S; Edinger Institute of Neurology, Goethe University Medical School, Frankfurt, Germany.
J Cereb Blood Flow Metab ; 36(7): 1281-94, 2016 07.
Article em En | MEDLINE | ID: mdl-26661166
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Endotélio Vascular / Barreira Hematoencefálica / Ácido Aspártico Endopeptidases / Secretases da Proteína Precursora do Amiloide / Doença de Alzheimer Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Endotélio Vascular / Barreira Hematoencefálica / Ácido Aspártico Endopeptidases / Secretases da Proteína Precursora do Amiloide / Doença de Alzheimer Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article