Effect of the pulse length of ultrasound on cell membrane damage in vitro.
J Acoust Soc Am
; 86(1): 6-7, 1989 Jul.
Article
em En
| MEDLINE
| ID: mdl-2666474
ABSTRACT
Suspended cells of a human lymphoblastic cell line were exposed to pulsed ultrasound of 775 kHz. The pulse lengths were varied between 16 and 1000 microseconds. The mark/space ratio was always kept at 11. Two ultrasound intensity levels were used 3.6 and 6.4 W/cm2 spatial peak and temporal peak. After an exposure time of 5 min, cell membrane damage was measured cytometrically by a dye exclusion test. No membrane damage was observable at 16 microseconds, whereas, at pulse lengths of 1000 microseconds, about one-third of the cells were damaged.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ultrassom
/
Células Tumorais Cultivadas
/
Ultrassonografia
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
1989
Tipo de documento:
Article