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Fusobacterium nucleatum infection of gingival epithelial cells leads to NLRP3 inflammasome-dependent secretion of IL-1ß and the danger signals ASC and HMGB1.
Bui, Fiona Q; Johnson, Larry; Roberts, JoAnn; Hung, Shu-Chen; Lee, Jungnam; Atanasova, Kalina Rosenova; Huang, Pei-Rong; Yilmaz, Özlem; Ojcius, David M.
Afiliação
  • Bui FQ; Department of Biomedical Sciences, University of the Pacific, Arthur Dugoni School of Dentistry, San Francisco, CA, 95343, USA.
  • Johnson L; Department of Biomedical Sciences, University of the Pacific, Arthur Dugoni School of Dentistry, San Francisco, CA, 95343, USA.
  • Roberts J; Immunobiology Program, Instituto de Biofísica Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, 21941, Brazil.
  • Hung SC; Department of Periodontology and Emerging Pathogens Institute, University of Florida, Gainesville, FL, 32610, USA.
  • Lee J; Department of Biomedical Sciences, University of the Pacific, Arthur Dugoni School of Dentistry, San Francisco, CA, 95343, USA.
  • Atanasova KR; Department of Periodontology and Emerging Pathogens Institute, University of Florida, Gainesville, FL, 32610, USA.
  • Huang PR; Department of Periodontology and Emerging Pathogens Institute, University of Florida, Gainesville, FL, 32610, USA.
  • Yilmaz Ö; Center for Molecular and Clinical Immunology, Chang Gung University, Gueishan, Taoyuan 333, Taiwan.
  • Ojcius DM; Department of Periodontology and Emerging Pathogens Institute, University of Florida, Gainesville, FL, 32610, USA.
Cell Microbiol ; 18(7): 970-81, 2016 07.
Article em En | MEDLINE | ID: mdl-26687842

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas do Citoesqueleto / Proteína HMGB1 / Interleucina-1beta / Infecções por Fusobacterium / Gengiva Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas do Citoesqueleto / Proteína HMGB1 / Interleucina-1beta / Infecções por Fusobacterium / Gengiva Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article