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Engineering an allosteric transcription factor to respond to new ligands.
Taylor, Noah D; Garruss, Alexander S; Moretti, Rocco; Chan, Sum; Arbing, Mark A; Cascio, Duilio; Rogers, Jameson K; Isaacs, Farren J; Kosuri, Sriram; Baker, David; Fields, Stanley; Church, George M; Raman, Srivatsan.
Afiliação
  • Taylor ND; Wyss Institute for Biologically-Inspired Engineering, Harvard University, Boston, Massachusetts, USA.
  • Garruss AS; Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.
  • Moretti R; Wyss Institute for Biologically-Inspired Engineering, Harvard University, Boston, Massachusetts, USA.
  • Chan S; Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.
  • Arbing MA; Department of Biochemistry, University of Washington, Seattle, Washington, USA.
  • Cascio D; Howard Hughes Medical Institute, University of Washington, Seattle, Washington, USA.
  • Rogers JK; University of California Los Angeles-Department of Energy Institute for Genomics and Proteomics, University of California Los Angeles, Los Angeles, California, USA.
  • Isaacs FJ; University of California Los Angeles-Department of Energy Institute for Genomics and Proteomics, University of California Los Angeles, Los Angeles, California, USA.
  • Kosuri S; University of California Los Angeles-Department of Energy Institute for Genomics and Proteomics, University of California Los Angeles, Los Angeles, California, USA.
  • Baker D; Wyss Institute for Biologically-Inspired Engineering, Harvard University, Boston, Massachusetts, USA.
  • Fields S; Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.
  • Church GM; Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, Connecticut, USA.
  • Raman S; Systems Biology Institute, Yale University, West Haven, Connecticut, USA.
Nat Methods ; 13(2): 177-83, 2016 Feb.
Article em En | MEDLINE | ID: mdl-26689263
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Engenharia Genética / Regulação Bacteriana da Expressão Gênica / Proteínas de Escherichia coli / Escherichia coli / Repressores Lac Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Engenharia Genética / Regulação Bacteriana da Expressão Gênica / Proteínas de Escherichia coli / Escherichia coli / Repressores Lac Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2016 Tipo de documento: Article