Spatially defined stem cell-laden hydrogel islands for directing endothelial tubulogenesis.
J Mater Chem B
; 3(40): 7896-7898, 2015 Oct 28.
Article
em En
| MEDLINE
| ID: mdl-26693014
ABSTRACT
The spatiotemporal coordination of angiogenesis in synthetic materials is important for mimicking natural tissue morphogenesis. Here we report patterned hydrogel encapsulation of mesenchymal stem cells to direct endothelial tubulogenesis in co-culture. Tubulogenesis occurs preferentially over MSC patterns, suggesting this strategy may prove useful in guiding the design of heterotypic engineered tissues.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article