PBN (Phenyl-N-Tert-Butylnitrone)-Derivatives Are Effective in Slowing the Visual Cycle and Rhodopsin Regeneration and in Protecting the Retina from Light-Induced Damage.

Stiles, Megan; Moiseyev, Gennadiy P; Budda, Madeline L; Linens, Annette; Brush, Richard S; Qi, Hui; White, Gary L; Wolf, Roman F; Ma, Jian-Xing; Floyd, Robert; Anderson, Robert E; Mandal, Nawajes A

Stiles, Megan; Moiseyev, Gennadiy P; Budda, Madeline L; Linens, Annette; Brush, Richard S; Qi, Hui; White, Gary L; Wolf, Roman F; Ma, Jian-Xing; Floyd, Robert; Anderson, Robert E; Mandal, Nawajes A.

Afiliação

Stiles M; Department of Ophthalmology, OUHSC, Oklahoma City, Oklahoma, United States of America.
Moiseyev GP; Dean McGee Eye Institute, Oklahoma City, Oklahoma, United States of America.
Budda ML; Department of Physiology, OUHSC, Oklahoma City, Oklahoma, United States of America.
Linens A; Department of Cell Biology, OUHSC, Oklahoma City, Oklahoma, United States of America.
Brush RS; Department of Ophthalmology, OUHSC, Oklahoma City, Oklahoma, United States of America.
Qi H; Dean McGee Eye Institute, Oklahoma City, Oklahoma, United States of America.
White GL; Department of Ophthalmology, OUHSC, Oklahoma City, Oklahoma, United States of America.
Wolf RF; Dean McGee Eye Institute, Oklahoma City, Oklahoma, United States of America.
Ma JX; Department of Ophthalmology, OUHSC, Oklahoma City, Oklahoma, United States of America.
Floyd R; Dean McGee Eye Institute, Oklahoma City, Oklahoma, United States of America.
Anderson RE; Department of Pathology, OUHSC, Oklahoma City, Oklahoma, United States of America.
Mandal NA; Department of Pathology, OUHSC, Oklahoma City, Oklahoma, United States of America.

PLoS One ; 10(12): e0145305, 2015.

Article em En | MEDLINE | ID: mdl-26694648

Assuntos

Óxidos N-Cíclicos/administração & dosagem; Luz/efeitos adversos; Doenças Retinianas/prevenção & controle; Epitélio Pigmentado da Retina/efeitos dos fármacos; Rodopsina/metabolismo; Animais; Bovinos; Óxidos N-Cíclicos/química; Óxidos N-Cíclicos/farmacologia; Feminino; Injeções Intraperitoneais; Masculino; Camundongos; Papio anubis; Ratos; Doenças Retinianas/etiologia; Doenças Retinianas/metabolismo; Epitélio Pigmentado da Retina/efeitos da radiação; cis-trans-Isomerases/antagonistas & inibidores; cis-trans-Isomerases/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Retinianas / Rodopsina / Óxidos N-Cíclicos / Epitélio Pigmentado da Retina / Luz Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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