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Novel Zn2+ Modulated GPR39 Receptor Agonists Do Not Drive Acute Insulin Secretion in Rodents.
Fjellström, Ola; Larsson, Niklas; Yasuda, Shin-Ichiro; Tsuchida, Takuma; Oguma, Takahiro; Marley, Anna; Wennberg-Huldt, Charlotte; Hovdal, Daniel; Fukuda, Hajime; Yoneyama, Yukimi; Sasaki, Kazuyo; Johansson, Anders; Lundqvist, Sara; Brengdahl, Johan; Isaacs, Richard J; Brown, Daniel; Geschwindner, Stefan; Benthem, Lambertus; Priest, Claire; Turnbull, Andrew.
Afiliação
  • Fjellström O; Medicinal Chemistry CVMD iMed, AstraZeneca R&D Gothenburg, Mölndal, Sweden.
  • Larsson N; Discovery Sciences, AstraZeneca R&D Gothenburg, Mölndal, Sweden.
  • Yasuda S; Pharmacology Research Laboratories II, Mitsubishi Tanabe Pharma Corporation, Kawagishi, Toda-shi, Saitama, Japan.
  • Tsuchida T; Pharmacology Research Laboratories II, Mitsubishi Tanabe Pharma Corporation, Kawagishi, Toda-shi, Saitama, Japan.
  • Oguma T; Pharmacology Research Laboratories II, Mitsubishi Tanabe Pharma Corporation, Kawagishi, Toda-shi, Saitama, Japan.
  • Marley A; Discovery Sciences, AstraZeneca R&D, Mereside, United Kingdom.
  • Wennberg-Huldt C; Bioscience CVMD iMed, AstraZeneca R&D Gothenburg, Mölndal, Sweden.
  • Hovdal D; DMPK CVMD iMed, AstraZeneca R&D Gothenburg, Mölndal, Sweden.
  • Fukuda H; DMPK Research Laboratories, Mitsubishi Tanabe Pharma Corporation, Kawagishi, Toda-shi, Saitama, Japan.
  • Yoneyama Y; DMPK Research Laboratories, Mitsubishi Tanabe Pharma Corporation, Kawagishi, Toda-shi, Saitama, Japan.
  • Sasaki K; Pharmacology Research Laboratories II, Mitsubishi Tanabe Pharma Corporation, Kawagishi, Toda-shi, Saitama, Japan.
  • Johansson A; Medicinal Chemistry CVMD iMed, AstraZeneca R&D Gothenburg, Mölndal, Sweden.
  • Lundqvist S; Discovery Sciences, AstraZeneca R&D Gothenburg, Mölndal, Sweden.
  • Brengdahl J; Discovery Sciences, AstraZeneca R&D Gothenburg, Mölndal, Sweden.
  • Isaacs RJ; Molecular Sensing, Inc., Nashville, Tennessee, United States of America.
  • Brown D; Molecular Sensing, Inc., Nashville, Tennessee, United States of America.
  • Geschwindner S; Discovery Sciences, AstraZeneca R&D Gothenburg, Mölndal, Sweden.
  • Benthem L; Bioscience CVMD iMed, AstraZeneca R&D Gothenburg, Mölndal, Sweden.
  • Priest C; Discovery Sciences, AstraZeneca R&D, Mereside, United Kingdom.
  • Turnbull A; CVMD iMed, AstraZeneca R&D Gothenburg, Mölndal, Sweden.
PLoS One ; 10(12): e0145849, 2015.
Article em En | MEDLINE | ID: mdl-26720709
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores Acoplados a Proteínas G / Descoberta de Drogas / Insulina Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores Acoplados a Proteínas G / Descoberta de Drogas / Insulina Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article