Mefloquine inhibits chondrocytic proliferation by arresting cell cycle in G2/M phase.

Li, Qiong; Chen, Zeng-Gan; Xia, Qing; Lin, Jian-Ping; Yan, Zuo-Qin; Yao, Zheng-Jun; Dong, Jian

Li, Qiong; Chen, Zeng-Gan; Xia, Qing; Lin, Jian-Ping; Yan, Zuo-Qin; Yao, Zheng-Jun; Dong, Jian.

Afiliação

Li Q; Department of Orthopedic Surgery, Zhongshan Hospital, Fudan University Shanghai, China.
Chen ZG; Department of Orthopedic Surgery, Zhongshan Hospital, Fudan University Shanghai, China.
Xia Q; Department of Orthopedic Surgery, Zhongshan Hospital, Fudan University Shanghai, China.
Lin JP; Department of Orthopedic Surgery, Zhongshan Hospital, Fudan University Shanghai, China.
Yan ZQ; Department of Orthopedic Surgery, Zhongshan Hospital, Fudan University Shanghai, China.
Yao ZJ; Department of Orthopedic Surgery, Zhongshan Hospital, Fudan University Shanghai, China.
Dong J; Department of Orthopedic Surgery, Zhongshan Hospital, Fudan University Shanghai, China.

Int J Clin Exp Pathol ; 8(10): 12583-8, 2015.

Article em En | MEDLINE | ID: mdl-26722448

Assuntos

Pontos de Checagem do Ciclo Celular/efeitos dos fármacos; Proliferação de Células/efeitos dos fármacos; Condrócitos/efeitos dos fármacos; Mefloquina/farmacologia; Animais; Apoptose/efeitos dos fármacos; Western Blotting; Células Cultivadas; Citometria de Fluxo; Masculino; Ratos; Ratos Wistar

Palavras-chave

Chondrocytes; cyclin B1; inhibition; mefloquine; proliferation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mefloquina / Condrócitos / Proliferação de Células / Pontos de Checagem do Ciclo Celular Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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