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The epidemiology of rotavirus disease in under-five-year-old children hospitalized with acute diarrhea in central Uganda, 2012-2013.
Bwogi, Josephine; Malamba, Samuel; Kigozi, Brian; Namuwulya, Prossy; Tushabe, Phionah; Kiguli, Sarah; Byarugaba, Denis Karuhize; Desselberger, Ulrich; Iturriza-Gomara, Miren; Karamagi, Charles.
Afiliação
  • Bwogi J; Uganda Virus Research Institute, 51-59 Nakiwogo Road, P.O. BOX 49, Entebbe, Uganda. josephinebwn@yahoo.co.uk.
  • Malamba S; Department of Paediatrics and Child Health, College of Health Sciences, Makerere University, P.O. BOX 7072, Kampala, Uganda. josephinebwn@yahoo.co.uk.
  • Kigozi B; Uganda Virus Research Institute, 51-59 Nakiwogo Road, P.O. BOX 49, Entebbe, Uganda.
  • Namuwulya P; Uganda Virus Research Institute, 51-59 Nakiwogo Road, P.O. BOX 49, Entebbe, Uganda.
  • Tushabe P; Uganda Virus Research Institute, 51-59 Nakiwogo Road, P.O. BOX 49, Entebbe, Uganda.
  • Kiguli S; Department of Paediatrics and Child Health, College of Health Sciences, Makerere University, P.O. BOX 7072, Kampala, Uganda.
  • Byarugaba DK; Department of Paediatrics and Child Health, College of Health Sciences, Makerere University, P.O. BOX 7072, Kampala, Uganda.
  • Desselberger U; Department of Microbiology, College of Veterinary Medicine and Biosecurity, Makerere University, P.O. BOX 7072, Kampala, Uganda.
  • Iturriza-Gomara M; Department of Medicine, University of Cambridge, Cambridge, CB2 0QQ, UK.
  • Karamagi C; Department of Clinical Infection, Microbiology and Immunology, Institute of Infection and Global Health, University of Liverpool, Ronald Ross Building, West Derby Street, Liverpool, L69 7BE, UK.
Arch Virol ; 161(4): 999-1003, 2016 Apr.
Article em En | MEDLINE | ID: mdl-26724820
ABSTRACT
A cross-sectional study was undertaken during 2012-2013 to determine the prevalence, strains and factors associated with rotavirus infection among under-5-year-old children hospitalized with acute diarrhea in Uganda. Rotaviruses were detected in 37 % (263/712) of the children. The most prevalent strains were G9P[8] (27 %, 55/204) and G12P[4] (18.6 %, 38/204). Mixed infections were detected in 22.5 % (46/204) of the children. The study suggests that consumption of raw vegetables (OR = 1.45, 95 % CI = 1.03-2.03) and family ownership of dogs (OR = 1.9, 95 % CI = 1.04-3.75) increases the risk of rotavirus infection. The study findings will be used to assess the impact of RV vaccination in Uganda.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções por Rotavirus Tipo de estudo: Etiology_studies / Observational_studies / Risk_factors_studies / Screening_studies Limite: Child, preschool / Female / Humans / Infant / Male País/Região como assunto: Africa Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções por Rotavirus Tipo de estudo: Etiology_studies / Observational_studies / Risk_factors_studies / Screening_studies Limite: Child, preschool / Female / Humans / Infant / Male País/Região como assunto: Africa Idioma: En Ano de publicação: 2016 Tipo de documento: Article