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Oxidative Dimerization of PHD2 is Responsible for its Inactivation and Contributes to Metabolic Reprogramming via HIF-1α Activation.
Lee, Gibok; Won, Hyung-Sik; Lee, Yoon-Mi; Choi, Jae-Wan; Oh, Taek-In; Jang, Jeong-Hwa; Choi, Dong-Kug; Lim, Beong-Ou; Kim, Young Jun; Park, Jong-Wan; Puigserver, Pere; Lim, Ji-Hong.
Afiliação
  • Lee G; Department of Biomedical Chemistry, College of Biomedical &Health Science, Konkuk University, Chungju 380-701, Chungbuk, Republic of Korea.
  • Won HS; Department of Biotechnology, College of Biomedical &Health Science, Konkuk University, Chungju 380-701, Chungbuk, Republic of Korea.
  • Lee YM; Department of Food Bioscience, College of Biomedical &Health Science, Konkuk University, Chungju 380-701, Chungbuk, Republic of Korea.
  • Choi JW; Department of Biotechnology, College of Biomedical &Health Science, Konkuk University, Chungju 380-701, Chungbuk, Republic of Korea.
  • Oh TI; Department of Biomedical Chemistry, College of Biomedical &Health Science, Konkuk University, Chungju 380-701, Chungbuk, Republic of Korea.
  • Jang JH; Department of Biotechnology, College of Biomedical &Health Science, Konkuk University, Chungju 380-701, Chungbuk, Republic of Korea.
  • Choi DK; Department of Biotechnology, College of Biomedical &Health Science, Konkuk University, Chungju 380-701, Chungbuk, Republic of Korea.
  • Lim BO; Department of Biomedical Chemistry, College of Biomedical &Health Science, Konkuk University, Chungju 380-701, Chungbuk, Republic of Korea.
  • Kim YJ; Department of Biomedical Chemistry, College of Biomedical &Health Science, Konkuk University, Chungju 380-701, Chungbuk, Republic of Korea.
  • Park JW; Department of Pharmacology, Seoul National University, College of Medicine, Seoul 110-799, Republic of Korea.
  • Puigserver P; Department of Cancer Biology, Dana-Farber Cancer Institute; Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA.
  • Lim JH; Department of Biomedical Chemistry, College of Biomedical &Health Science, Konkuk University, Chungju 380-701, Chungbuk, Republic of Korea.
Sci Rep ; 6: 18928, 2016 Jan 07.
Article em En | MEDLINE | ID: mdl-26740011
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estresse Oxidativo / Subunidade alfa do Fator 1 Induzível por Hipóxia / Prolina Dioxigenases do Fator Induzível por Hipóxia Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estresse Oxidativo / Subunidade alfa do Fator 1 Induzível por Hipóxia / Prolina Dioxigenases do Fator Induzível por Hipóxia Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article