Exercise Induces Peripheral Muscle But Not Cardiac Adaptations After Stroke: A Randomized Controlled Pilot Trial.
Arch Phys Med Rehabil
; 97(4): 596-603, 2016 Apr.
Article
em En
| MEDLINE
| ID: mdl-26763949
ABSTRACT
OBJECTIVE:
To explore the physiological factors affecting exercise-induced changes in peak oxygen consumption and function poststroke.DESIGN:
Single-center, single-blind, randomized controlled pilot trial.SETTING:
Community stroke services.PARTICIPANTS:
Adults (N=40; age>50y; independent with/without stick) with stroke (diagnosed >6 mo previously) were recruited from 117 eligible participants. Twenty participants were randomized to the intervention group and 20 to the control group. No dropouts or adverse events were reported.INTERVENTIONS:
Intervention group 19-week (3 times/wk) progressive mixed (aerobic/strength/balance/flexibility) community group exercise program. Control group Matched duration home stretching program. MAIN OUTCOMEMEASURES:
(1) Pre- and postintervention maximal cardiopulmonary exercise testing with noninvasive (bioreactance) cardiac output measurements; and (2) functional outcomemeasures:
6-minute walk test; timed Up and Go test, and Berg Balance Scale.RESULTS:
Exercise improved peak oxygen consumption (18±5 to 21±5 mL/(kgâ min); P<.01) and peak arterial-venous oxygen difference (9.2±2.7 to 11.4±2.9 mL of O2/100 mL of blood; P<.01), but did not alter cardiac output (17.2±4 to 17.7±4.2 L/min; P=.44) or cardiac power output (4.8±1.3 to 5.0±1.35 W; P=.45). A significant relation existed between change in peak oxygen consumption and change in peak arterial-venous oxygen difference (r=.507; P<.05), but not with cardiac output. Change in peak oxygen consumption did not strongly correlate with change in function.CONCLUSIONS:
Exercise induced peripheral muscle, but not cardiac output, adaptations after stroke. Implications for stroke clinical care should be explored further in a broader cohort.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Débito Cardíaco
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Exercício Físico
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Músculo Esquelético
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Acidente Vascular Cerebral
Tipo de estudo:
Clinical_trials
Limite:
Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article