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Autoimmune vitiligo is associated with gain-of-function by a transcriptional regulator that elevates expression of HLA-A*02:01 in vivo.
Hayashi, Masahiro; Jin, Ying; Yorgov, Daniel; Santorico, Stephanie A; Hagman, James; Ferrara, Tracey M; Jones, Kenneth L; Cavalli, Giulio; Dinarello, Charles A; Spritz, Richard A.
Afiliação
  • Hayashi M; Human Medical Genetics and Genomics Program, University of Colorado School of Medicine, Aurora, CO 80045;
  • Jin Y; Human Medical Genetics and Genomics Program, University of Colorado School of Medicine, Aurora, CO 80045; Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO 80045;
  • Yorgov D; Department of Mathematical & Statistical Science, University of Colorado Denver, Denver, CO 80217;
  • Santorico SA; Human Medical Genetics and Genomics Program, University of Colorado School of Medicine, Aurora, CO 80045; Department of Mathematical & Statistical Science, University of Colorado Denver, Denver, CO 80217;
  • Hagman J; Department of Biomedical Research, National Jewish Health, Denver, CO 80206; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO 80045;
  • Ferrara TM; Human Medical Genetics and Genomics Program, University of Colorado School of Medicine, Aurora, CO 80045; Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO 80045;
  • Jones KL; Department of Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora, CO 80045;
  • Cavalli G; Department of Medicine, University of Colorado School of Medicine, Aurora, CO 80045; Internal Medicine and Clinical Immunology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) San Raffaele Scientific Institute and Vita-Salute San Raffaele University, 20129 Milan, Italy.
  • Dinarello CA; Department of Medicine, University of Colorado School of Medicine, Aurora, CO 80045; cdinare333@aol.com richard.spritz@ucdenver.edu.
  • Spritz RA; Human Medical Genetics and Genomics Program, University of Colorado School of Medicine, Aurora, CO 80045; Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO 80045; cdinare333@aol.com richard.spritz@ucdenver.edu.
Proc Natl Acad Sci U S A ; 113(5): 1357-62, 2016 Feb 02.
Article em En | MEDLINE | ID: mdl-26787886
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Autoimunes / Transcrição Gênica / Vitiligo / Antígenos HLA-A / Regulação da Expressão Gênica Tipo de estudo: Prognostic_studies / Qualitative_research / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Autoimunes / Transcrição Gênica / Vitiligo / Antígenos HLA-A / Regulação da Expressão Gênica Tipo de estudo: Prognostic_studies / Qualitative_research / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article