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A dose escalating phase I study of GLPG0187, a broad spectrum integrin receptor antagonist, in adult patients with progressive high-grade glioma and other advanced solid malignancies.
Cirkel, Geert A; Kerklaan, Bojana Milojkovic; Vanhoutte, Frédéric; Van der Aa, Annegret; Lorenzon, Giocondo; Namour, Florence; Pujuguet, Philippe; Darquenne, Sophie; de Vos, Filip Y F; Snijders, Tom J; Voest, Emile E; Schellens, Jan H M; Lolkema, Martijn P.
Afiliação
  • Cirkel GA; Department of Medical Oncology, University Medical Center Utrecht, Heidelberglaan 100, 3584, CX Utrecht, The Netherlands.
  • Kerklaan BM; Department of Clinical Pharmacology, Netherlands Cancer Institute, Plesmanlaan 121, 1066, CX Amsterdam, The Netherlands.
  • Vanhoutte F; Galapagos NV, Gen. De Wittelaan L11A3, 2800, Mechelen, Belgium.
  • Van der Aa A; Galapagos NV, Gen. De Wittelaan L11A3, 2800, Mechelen, Belgium.
  • Lorenzon G; Galapagos SASU, 102 Avenue Gaston Roussel, 93230, Romainville, France.
  • Namour F; Galapagos SASU, 102 Avenue Gaston Roussel, 93230, Romainville, France.
  • Pujuguet P; Galapagos SASU, 102 Avenue Gaston Roussel, 93230, Romainville, France.
  • Darquenne S; Galapagos SASU, 102 Avenue Gaston Roussel, 93230, Romainville, France.
  • de Vos FY; Department of Medical Oncology, University Medical Center Utrecht, Heidelberglaan 100, 3584, CX Utrecht, The Netherlands.
  • Snijders TJ; Brain Center Rudolf Magnus, Department of Neurology and Neurosurgery, University Medical Center Utrecht, Heidelberglaan 100, 3584, CX Utrecht, The Netherlands.
  • Voest EE; Department of Medical Oncology, University Medical Center Utrecht, Heidelberglaan 100, 3584, CX Utrecht, The Netherlands.
  • Schellens JH; Netherlands Cancer Institute, Plesmanlaan 121, PO box: 90203, 1006, BE Amsterdam, The Netherlands.
  • Lolkema MP; Department of Clinical Pharmacology, Netherlands Cancer Institute, Plesmanlaan 121, 1066, CX Amsterdam, The Netherlands.
Invest New Drugs ; 34(2): 184-92, 2016 Apr.
Article em En | MEDLINE | ID: mdl-26792581
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridinas / Sulfonamidas / Neoplasias Encefálicas / Receptores de Superfície Celular / Glioma / Naftiridinas Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridinas / Sulfonamidas / Neoplasias Encefálicas / Receptores de Superfície Celular / Glioma / Naftiridinas Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2016 Tipo de documento: Article