NAD(P)H: quinone oxidoreductase 1 inducer activity of novel 4-aminoquinazoline derivatives.

Ghorab, Mostafa M; Alsaid, Mansour S; El-Gazzar, Marwa G; Higgins, Maureen; Dinkova-Kostova, Albena T; Shahat, Abdelaaty A

Ghorab, Mostafa M; Alsaid, Mansour S; El-Gazzar, Marwa G; Higgins, Maureen; Dinkova-Kostova, Albena T; Shahat, Abdelaaty A.

Afiliação

Ghorab MM; a Department of Pharmacognosy , College of Pharmacy, King Saud University , Riyadh , Kingdom of Saudi Arabia .
Alsaid MS; b Department of Drug Radiation Research , National Center for Radiation Research and Technology, Atomic Energy Authority , Nasr City , Cairo , Egypt .
El-Gazzar MG; a Department of Pharmacognosy , College of Pharmacy, King Saud University , Riyadh , Kingdom of Saudi Arabia .
Higgins M; b Department of Drug Radiation Research , National Center for Radiation Research and Technology, Atomic Energy Authority , Nasr City , Cairo , Egypt .
Dinkova-Kostova AT; c Jacqui Wood Cancer Centre, Division of Cancer Research, Medical Research Institute, University of Dundee , Dundee , UK .
Shahat AA; c Jacqui Wood Cancer Centre, Division of Cancer Research, Medical Research Institute, University of Dundee , Dundee , UK .

J Enzyme Inhib Med Chem ; 31(6): 1369-74, 2016 Dec.

Article em En | MEDLINE | ID: mdl-26796666

Assuntos

Indução Enzimática/efeitos dos fármacos; NAD(P)H Desidrogenase (Quinona)/biossíntese; Animais; Linhagem Celular; Camundongos; Quinazolinas/farmacologia; Análise Espectral/métodos

Palavras-chave

4-aminoquinazoline; NAD(P)H; cytoprotective; synthesis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Indução Enzimática / NAD(P)H Desidrogenase (Quinona) Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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