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Biokinetic studies of non-complexed siRNA versus nano-sized PEI F25-LMW/siRNA polyplexes following intratracheal instillation into mice.
Lipka, Jens; Semmler-Behnke, Manuela; Wenk, Alexander; Burkhardt, Jana; Aigner, Achim; Kreyling, Wolfgang.
Afiliação
  • Lipka J; Comprehensive Pneumology Center, Institute of Lung Biology and Disease, Helmholtz Zentrum München-German Research Center for Environmental Health, Ingolstaedter Landstraße 1, 85764 Neuherberg, Germany; Philipps-University of Marburg, Department of Pharmaceutics and Biopharmacy, Ketzerbach 63, 35037
  • Semmler-Behnke M; Comprehensive Pneumology Center, Institute of Lung Biology and Disease, Helmholtz Zentrum München-German Research Center for Environmental Health, Ingolstaedter Landstraße 1, 85764 Neuherberg, Germany.
  • Wenk A; Comprehensive Pneumology Center, Institute of Lung Biology and Disease, Helmholtz Zentrum München-German Research Center for Environmental Health, Ingolstaedter Landstraße 1, 85764 Neuherberg, Germany.
  • Burkhardt J; Fraunhofer Institute for Cell Therapy and Immunology (IZI) Leipzig, Perlickstraße 1, 04103 Leipzig, Germany.
  • Aigner A; Rudolf-Boehm-Institute for Pharmacology and Toxicology, Clinical Pharmacology, University of Leipzig, Haertelstrasse 16-18, 04107 Leipzig, Germany.
  • Kreyling W; Comprehensive Pneumology Center, Institute of Lung Biology and Disease, Helmholtz Zentrum München-German Research Center for Environmental Health, Ingolstaedter Landstraße 1, 85764 Neuherberg, Germany. Electronic address: kreyling@helmholtz-muenchen.de.
Int J Pharm ; 500(1-2): 227-35, 2016 Mar 16.
Article em En | MEDLINE | ID: mdl-26802492
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polietilenoimina / RNA Interferente Pequeno / Nanopartículas Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polietilenoimina / RNA Interferente Pequeno / Nanopartículas Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article