Photoresponsive Formation of an Intermolecular Minimal G-Quadruplex Motif.
Angew Chem Int Ed Engl
; 55(8): 2738-42, 2016 Feb 18.
Article
em En
| MEDLINE
| ID: mdl-26805928
ABSTRACT
The ability of three different bifunctional azobenzene linkers to enable the photoreversible formation of a defined intermolecular two-tetrad G-quadruplex upon UV/Vis irradiation was investigated. Circular dichroism and NMR spectroscopic data showed the formation of G-quadruplexes with K(+) â
ions at room temperature in all three cases with the corresponding azobenzene linker in an Eâ
conformation. However, only the para-para-substituted azobenzene derivative enables photoswitching between a nonpolymorphic, stacked, tetramolecular G-quadruplex and an unstructured state after E-Zâ
isomerization.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Quadruplex G
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article