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A Complex Network of Interactions between S282 and G283 of Hepatitis C Virus Nonstructural Protein 5B and the Template Strand Affects Susceptibility to Sofosbuvir and Ribavirin.
Kulkarni, Anupriya S; Damha, Masad J; Schinazi, Raymond F; Mo, Hongmei; Doehle, Brian; Sagan, Selena M; Götte, Matthias.
Afiliação
  • Kulkarni AS; Department of Microbiology and Immunology, McGill University, Montreal, Quebec, Canada.
  • Damha MJ; Department of Chemistry, McGill University, Montreal, Quebec, Canada.
  • Schinazi RF; Center for AIDS Research, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Veterans Affairs Medical Center, Atlanta, Georgia, USA.
  • Mo H; Gilead Sciences, Inc., Foster City, California, USA.
  • Doehle B; Gilead Sciences, Inc., Foster City, California, USA.
  • Sagan SM; Department of Microbiology and Immunology, McGill University, Montreal, Quebec, Canada.
  • Götte M; Department of Microbiology and Immunology, McGill University, Montreal, Quebec, Canada Department of Biochemistry, McGill University, Montreal, Quebec, Canada Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta, Canada gotte@ualberta.ca.
Antimicrob Agents Chemother ; 60(4): 2018-27, 2016 Apr.
Article em En | MEDLINE | ID: mdl-26824949
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Ribavirina / RNA Viral / Proteínas não Estruturais Virais / Hepacivirus / Sofosbuvir Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Ribavirina / RNA Viral / Proteínas não Estruturais Virais / Hepacivirus / Sofosbuvir Idioma: En Ano de publicação: 2016 Tipo de documento: Article