Acidic pH-Induced Conformations and LAMP1 Binding of the Lassa Virus Glycoprotein Spike.

Li, Sai; Sun, Zhaoyang; Pryce, Rhys; Parsy, Marie-Laure; Fehling, Sarah K; Schlie, Katrin; Siebert, C Alistair; Garten, Wolfgang; Bowden, Thomas A; Strecker, Thomas; Huiskonen, Juha T

Li, Sai; Sun, Zhaoyang; Pryce, Rhys; Parsy, Marie-Laure; Fehling, Sarah K; Schlie, Katrin; Siebert, C Alistair; Garten, Wolfgang; Bowden, Thomas A; Strecker, Thomas; Huiskonen, Juha T.

Afiliação

Li S; Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
Sun Z; Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
Pryce R; Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
Parsy ML; Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
Fehling SK; Institute of Virology, Philipps Universität Marburg, Marburg, Germany.
Schlie K; Institute of Virology, Philipps Universität Marburg, Marburg, Germany.
Siebert CA; Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
Garten W; Institute of Virology, Philipps Universität Marburg, Marburg, Germany.
Bowden TA; Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
Strecker T; Institute of Virology, Philipps Universität Marburg, Marburg, Germany.
Huiskonen JT; Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.

PLoS Pathog ; 12(2): e1005418, 2016 Feb.

Article em En | MEDLINE | ID: mdl-26849049

Assuntos

Glicoproteínas/metabolismo; Vírus Lassa/metabolismo; Proteínas de Membrana Lisossomal/metabolismo; Sinais Direcionadores de Proteínas; Proteínas do Envelope Viral/metabolismo; Animais; Chlorocebus aethiops; Glicoproteínas/química; Concentração de Íons de Hidrogênio; Vírus Lassa/química; Vírus Lassa/ultraestrutura; Proteínas de Membrana Lisossomal/química; Modelos Moleculares; Conformação Molecular; Complexos Multiproteicos; Ligação Proteica; Estrutura Terciária de Proteína; Células Vero; Proteínas do Envelope Viral/química; Vírion; Internalização do Vírus

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sinais Direcionadores de Proteínas / Glicoproteínas / Proteínas do Envelope Viral / Proteínas de Membrana Lisossomal / Vírus Lassa Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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