[Proteomics and PCOS: Is it here the missing link? Literature review]. / Proteómica y síndrome de ovario poliquístico: ¿encontraremos aquí el eslabón perdido? Revisión de la bibliografía.
Ginecol Obstet Mex
; 83(10): 614-26, 2015 Oct.
Article
em Es
| MEDLINE
| ID: mdl-26859923
ABSTRACT
Polycystic ovary syndrome (PCOS) is known as a common gynecologic and endocrinology disease with multiple short and long-term consequences. It is one of the most common causes for hyperandrogenism and anovulation, increases the risk for metabolic syndrome, type 2 diabetes and cardiovascular disease. Its etiology remains unclear. PCOS is thought to be the result of the interaction between predisposing genetic variants with environmental factors and strongly depends on ethnicity. Proteomics allows the study of several hundreds or thousands of proteins in order to reveal physiological state of a tissue or an organ at the molecular level and to identify disease-specific biomarkers. Its use on PCOS patients will permit us to identify molecules that are involved in the PCOS pathology so we can develop specific diagnostic and management approaches.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Síndrome do Ovário Policístico
/
Biomarcadores
/
Proteômica
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
Limite:
Female
/
Humans
Idioma:
Es
Ano de publicação:
2015
Tipo de documento:
Article