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Molecular surveillance of antimalarial drug resistance related genes in Plasmodium falciparum isolates from Eritrea.
Menegon, Michela; Nurahmed, Abduselam M; Talha, Albadawi A; Nour, Bakri Y M; Severini, Carlo.
Afiliação
  • Menegon M; Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanità, Viale Regina Elena, 299, 00161 Rome, Italy. Electronic address: michela.menegon@iss.it.
  • Nurahmed AM; Faculty of Medical Laboratory Sciences, University of Gezira, P.O. Box 20, Wad Medani, Sudan. Electronic address: peace.abdu@gmail.com.
  • Talha AA; Faculty of Medical Laboratory Sciences, University of Gezira, P.O. Box 20, Wad Medani, Sudan. Electronic address: badawiat@yahoo.com.
  • Nour BY; Blue Nile Research National Institute for Communicable Diseases, University of Gezira, P.O. Box 20, Wad Medani, Sudan. Electronic address: bakrinour@gmail.com.
  • Severini C; Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanità, Viale Regina Elena, 299, 00161 Rome, Italy. Electronic address: carlo.severini@iss.it.
Acta Trop ; 157: 158-61, 2016 May.
Article em En | MEDLINE | ID: mdl-26875763
ABSTRACT
The introduction of artemisinin-based combination therapy has led to extraordinary results in malaria control, however the recent emergence of partial resistance to artemisinin therapy in Southeast Asia jeopardizes these successes. This study aimed at investigating resistance to the antimalarial drugs by evaluating the polymorphisms in the PfK13, Pfcrt and Pfmdr1 genes in Plasmodium falciparum isolates obtained from patients in Eritrea.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Resistência a Medicamentos / Malária Falciparum / Genes de Protozoários / Artemisininas / Antimaláricos Tipo de estudo: Prevalence_studies / Risk_factors_studies / Screening_studies Limite: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged País/Região como assunto: Africa Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Resistência a Medicamentos / Malária Falciparum / Genes de Protozoários / Artemisininas / Antimaláricos Tipo de estudo: Prevalence_studies / Risk_factors_studies / Screening_studies Limite: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged País/Região como assunto: Africa Idioma: En Ano de publicação: 2016 Tipo de documento: Article