Regulator of G Protein Signaling 7 (RGS7) Can Exist in a Homo-oligomeric Form That Is Regulated by G&#945;o and R7-binding Protein.

Tayou, Junior; Wang, Qiang; Jang, Geeng-Fu; Pronin, Alexey N; Orlandi, Cesare; Martemyanov, Kirill A; Crabb, John W; Slepak, Vladlen Z

Regulator of G Protein Signaling 7 (RGS7) Can Exist in a Homo-oligomeric Form That Is Regulated by Gαo and R7-binding Protein.

Tayou, Junior; Wang, Qiang; Jang, Geeng-Fu; Pronin, Alexey N; Orlandi, Cesare; Martemyanov, Kirill A; Crabb, John W; Slepak, Vladlen Z.

Afiliação

Tayou J; From the Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, Florida 33136.
Wang Q; From the Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, Florida 33136.
Jang GF; the Cole Eye Institute Cleveland Clinic, Cleveland, Ohio 44195, and.
Pronin AN; From the Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, Florida 33136.
Orlandi C; the Department of Neuroscience, Scripps Research Institute, Jupiter, Florida 33458.
Martemyanov KA; the Department of Neuroscience, Scripps Research Institute, Jupiter, Florida 33458.
Crabb JW; the Cole Eye Institute Cleveland Clinic, Cleveland, Ohio 44195, and.
Slepak VZ; From the Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, Florida 33136, VSlepak@med.miami.edu.

J Biol Chem ; 291(17): 9133-47, 2016 Apr 22.

Article em En | MEDLINE | ID: mdl-26895961

Assuntos

Proteínas de Transporte/metabolismo; Subunidades alfa Gi-Go de Proteínas de Ligação ao GTP/metabolismo; Multimerização Proteica/fisiologia; Proteínas RGS/metabolismo; Animais; Proteínas de Transporte/genética; Subunidades alfa Gi-Go de Proteínas de Ligação ao GTP/genética; Humanos; Peptídeos e Proteínas de Sinalização Intracelular; Camundongos; Camundongos Knockout; Proteínas RGS/genética

Palavras-chave

G protein; G protein-coupled receptor (GPCR); R7-binding protein (R7BP); immunoprecipitation; oligomer; protein cross-linking; regulator of G protein signaling (RGS); subcellular localization

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Transporte / Subunidades alfa Gi-Go de Proteínas de Ligação ao GTP / Proteínas RGS / Multimerização Proteica Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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