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Comprehensive Structure-Activity Relationship of Triantennary N-Acetylgalactosamine Conjugated Antisense Oligonucleotides for Targeted Delivery to Hepatocytes.
Prakash, Thazha P; Yu, Jinghua; Migawa, Michael T; Kinberger, Garth A; Wan, W Brad; Østergaard, Michael E; Carty, Recaldo L; Vasquez, Guillermo; Low, Audrey; Chappell, Alfred; Schmidt, Karsten; Aghajan, Mariam; Crosby, Jeff; Murray, Heather M; Booten, Sheri L; Hsiao, Jill; Soriano, Armand; Machemer, Todd; Cauntay, Patrick; Burel, Sebastien A; Murray, Susan F; Gaus, Hans; Graham, Mark J; Swayze, Eric E; Seth, Punit P.
Afiliação
  • Prakash TP; Ionis Pharmaceuticals Inc. , 2855 Gazelle Court, Carlsbad, California 92010, United States.
  • Yu J; Ionis Pharmaceuticals Inc. , 2855 Gazelle Court, Carlsbad, California 92010, United States.
  • Migawa MT; Ionis Pharmaceuticals Inc. , 2855 Gazelle Court, Carlsbad, California 92010, United States.
  • Kinberger GA; Ionis Pharmaceuticals Inc. , 2855 Gazelle Court, Carlsbad, California 92010, United States.
  • Wan WB; Ionis Pharmaceuticals Inc. , 2855 Gazelle Court, Carlsbad, California 92010, United States.
  • Østergaard ME; Ionis Pharmaceuticals Inc. , 2855 Gazelle Court, Carlsbad, California 92010, United States.
  • Carty RL; Ionis Pharmaceuticals Inc. , 2855 Gazelle Court, Carlsbad, California 92010, United States.
  • Vasquez G; Ionis Pharmaceuticals Inc. , 2855 Gazelle Court, Carlsbad, California 92010, United States.
  • Low A; Ionis Pharmaceuticals Inc. , 2855 Gazelle Court, Carlsbad, California 92010, United States.
  • Chappell A; Ionis Pharmaceuticals Inc. , 2855 Gazelle Court, Carlsbad, California 92010, United States.
  • Schmidt K; Ionis Pharmaceuticals Inc. , 2855 Gazelle Court, Carlsbad, California 92010, United States.
  • Aghajan M; Ionis Pharmaceuticals Inc. , 2855 Gazelle Court, Carlsbad, California 92010, United States.
  • Crosby J; Ionis Pharmaceuticals Inc. , 2855 Gazelle Court, Carlsbad, California 92010, United States.
  • Murray HM; Ionis Pharmaceuticals Inc. , 2855 Gazelle Court, Carlsbad, California 92010, United States.
  • Booten SL; Ionis Pharmaceuticals Inc. , 2855 Gazelle Court, Carlsbad, California 92010, United States.
  • Hsiao J; Ionis Pharmaceuticals Inc. , 2855 Gazelle Court, Carlsbad, California 92010, United States.
  • Soriano A; Ionis Pharmaceuticals Inc. , 2855 Gazelle Court, Carlsbad, California 92010, United States.
  • Machemer T; Ionis Pharmaceuticals Inc. , 2855 Gazelle Court, Carlsbad, California 92010, United States.
  • Cauntay P; Ionis Pharmaceuticals Inc. , 2855 Gazelle Court, Carlsbad, California 92010, United States.
  • Burel SA; Ionis Pharmaceuticals Inc. , 2855 Gazelle Court, Carlsbad, California 92010, United States.
  • Murray SF; Ionis Pharmaceuticals Inc. , 2855 Gazelle Court, Carlsbad, California 92010, United States.
  • Gaus H; Ionis Pharmaceuticals Inc. , 2855 Gazelle Court, Carlsbad, California 92010, United States.
  • Graham MJ; Ionis Pharmaceuticals Inc. , 2855 Gazelle Court, Carlsbad, California 92010, United States.
  • Swayze EE; Ionis Pharmaceuticals Inc. , 2855 Gazelle Court, Carlsbad, California 92010, United States.
  • Seth PP; Ionis Pharmaceuticals Inc. , 2855 Gazelle Court, Carlsbad, California 92010, United States.
J Med Chem ; 59(6): 2718-33, 2016 Mar 24.
Article em En | MEDLINE | ID: mdl-26914862
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Acetilgalactosamina / Oligonucleotídeos Antissenso / Hepatócitos Tipo de estudo: Guideline / Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Acetilgalactosamina / Oligonucleotídeos Antissenso / Hepatócitos Tipo de estudo: Guideline / Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2016 Tipo de documento: Article