Mitogen-activated protein kinase signaling causes malignant melanoma cells to differentially alter extracellular matrix biosynthesis to promote cell survival.

Afasizheva, Anna; Devine, Alexus; Tillman, Heather; Fung, King Leung; Vieira, Wilfred D; Blehm, Benjamin H; Kotobuki, Yorihisa; Busby, Ben; Chen, Emily I; Tanner, Kandice

Afasizheva, Anna; Devine, Alexus; Tillman, Heather; Fung, King Leung; Vieira, Wilfred D; Blehm, Benjamin H; Kotobuki, Yorihisa; Busby, Ben; Chen, Emily I; Tanner, Kandice.

Afiliação

Afasizheva A; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 37 Convent Dr., Bethesda, MD, 20892, USA. anyarus@gmail.com.
Devine A; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 37 Convent Dr., Bethesda, MD, 20892, USA. alexus.devine@nih.gov.
Tillman H; Laboratories of Genitourinary Cancer Pathogenesis, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 37 Convent Dr., Bethesda, 20892, MD, USA. heather.tillman@nih.gov.
Fung KL; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 37 Convent Dr., Bethesda, MD, 20892, USA. fungk@nih.gov.
Vieira WD; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 37 Convent Dr., Bethesda, MD, 20892, USA. vieiraw@pop.nci.nih.gov.
Blehm BH; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 37 Convent Dr., Bethesda, MD, 20892, USA. benblehm@gmail.com.
Kotobuki Y; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 37 Convent Dr., Bethesda, MD, 20892, USA. yorihisa8986@yahoo.co.jp.
Busby B; National Centers for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, 20892, MD, USA. ben.busby@gmail.com.
Chen EI; Proteomics Shared Resource at the Herbert Irving Comprehensive Cancer Center & Department of Pharmacology, Columbia University Medical Center, New York, 10032, NY, USA. ec2974@icg.cpmc.columbia.edu.
Tanner K; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 37 Convent Dr., Bethesda, MD, 20892, USA. kandice.tanner@nih.gov.

BMC Cancer ; 16: 186, 2016 Mar 05.

Article em En | MEDLINE | ID: mdl-26944546

Assuntos

Matriz Extracelular/metabolismo; Melanoma/metabolismo; Proteínas Quinases Ativadas por Mitógeno/metabolismo; Transdução de Sinais; Animais; Antineoplásicos/farmacologia; Antineoplásicos/uso terapêutico; Linhagem Celular Tumoral; Movimento Celular; Sobrevivência Celular; Modelos Animais de Doenças; Resistencia a Medicamentos Antineoplásicos; Proteínas da Matriz Extracelular/metabolismo; Feminino; Fibronectinas/metabolismo; Xenoenxertos; Humanos; Melanoma/tratamento farmacológico; Melanoma/patologia; Proteínas Quinases Ativadas por Mitógeno/antagonistas & inibidores; Metástase Neoplásica; Inibidores de Proteínas Quinases/farmacologia; Inibidores de Proteínas Quinases/uso terapêutico; Tenascina/metabolismo; Microambiente Tumoral

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Proteínas Quinases Ativadas por Mitógeno / Matriz Extracelular / Melanoma Tipo de estudo: Etiology_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google