Leptin promotes apoptosis and inhibits autophagy of chondrocytes through upregulating lysyl oxidase-like 3 during osteoarthritis pathogenesis.

Huang, Z M; Du, S H; Huang, L G; Li, J H; Xiao, L; Tong, P

Huang, Z M; Du, S H; Huang, L G; Li, J H; Xiao, L; Tong, P.

Afiliação

Huang ZM; Department of Orthopaedic Surgery, Xiaoshan Chinese Medical Hospital, China; Department of Orthopaedic Surgery, Affiliated Jiangnan Hospital of Zhejiang Chinese Medical University, China; Zhejiang Chinese Medical University, China; Institute of Orthopaedics and Traumatology of Zhejiang Province, Chi
Du SH; Department of Orthopedic Surgery, the Second Affiliated Hospital, School of Medicine, Zhejiang University, China.
Huang LG; Zhejiang Chinese Medical University, China.
Li JH; Department of Orthopaedic Surgery, Xiaoshan Chinese Medical Hospital, China.
Xiao L; Zhejiang Chinese Medical University, China; Institute of Orthopaedics and Traumatology of Zhejiang Province, China; Department of Orthopaedic Surgery, the First Affiliated Hospital of Zhejiang Chinese Medical University, China.
Tong P; Zhejiang Chinese Medical University, China; Institute of Orthopaedics and Traumatology of Zhejiang Province, China; Department of Orthopaedic Surgery, the First Affiliated Hospital of Zhejiang Chinese Medical University, China. Electronic address: pjtongzj@sina.com.

Osteoarthritis Cartilage ; 24(7): 1246-53, 2016 07.

Article em En | MEDLINE | ID: mdl-26947886

Assuntos

Apoptose; Animais; Autofagia; Cartilagem Articular; Condrócitos; Humanos; Leptina; Osteoartrite; Proteína-Lisina 6-Oxidase; Ratos

Palavras-chave

Apoptosis; Autophagy; LOXL3; Leptin; Osteoarthritis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Apoptose Tipo de estudo: Etiology_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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