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TGF-ß activates APC through Cdh1 binding for Cks1 and Skp2 proteasomal destruction stabilizing p27kip1 for normal endometrial growth.
Pavlides, Savvas C; Lecanda, Jon; Daubriac, Julien; Pandya, Unnati M; Gama, Patricia; Blank, Stephanie; Mittal, Khushbakhat; Shukla, Pratibha; Gold, Leslie I.
Afiliação
  • Pavlides SC; a Department of Medicine , New York University School of Medicine Langone Medical Center , New York , NY , USA.
  • Lecanda J; b Divisions of Translational Medicine , New York University School of Medicine Langone Medical Center , New York , NY , USA.
  • Daubriac J; a Department of Medicine , New York University School of Medicine Langone Medical Center , New York , NY , USA.
  • Pandya UM; b Divisions of Translational Medicine , New York University School of Medicine Langone Medical Center , New York , NY , USA.
  • Gama P; a Department of Medicine , New York University School of Medicine Langone Medical Center , New York , NY , USA.
  • Blank S; b Divisions of Translational Medicine , New York University School of Medicine Langone Medical Center , New York , NY , USA.
  • Mittal K; a Department of Medicine , New York University School of Medicine Langone Medical Center , New York , NY , USA.
  • Shukla P; b Divisions of Translational Medicine , New York University School of Medicine Langone Medical Center , New York , NY , USA.
  • Gold LI; c Department of Cell and Developmental Biology , Institute of Biomedical Sciences, University of Sao Paolo , Brazil.
Cell Cycle ; 15(7): 931-47, 2016.
Article em En | MEDLINE | ID: mdl-26963853

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator de Crescimento Transformador beta / Neoplasias do Endométrio / Quinases relacionadas a CDC2 e CDC28 / Proteínas Quinases Associadas a Fase S / Inibidor de Quinase Dependente de Ciclina p27 / Ciclossomo-Complexo Promotor de Anáfase Limite: Female / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator de Crescimento Transformador beta / Neoplasias do Endométrio / Quinases relacionadas a CDC2 e CDC28 / Proteínas Quinases Associadas a Fase S / Inibidor de Quinase Dependente de Ciclina p27 / Ciclossomo-Complexo Promotor de Anáfase Limite: Female / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article