New role and molecular mechanism of Gadd45a in hepatic ï¬brosis.

Hong, Liang; Sun, Qing-Feng; Xu, Ting-Yan; Wu, Yang-He; Zhang, Hui; Fu, Rong-Quan; Cai, Fu-Jing; Zhou, Qing-Qing; Zhou, Ke; Du, Qing-Wei; Zhang, Dong; Xu, Shuang; Ding, Ji-Guang

New role and molecular mechanism of Gadd45a in hepatic ï¬brosis.

Hong, Liang; Sun, Qing-Feng; Xu, Ting-Yan; Wu, Yang-He; Zhang, Hui; Fu, Rong-Quan; Cai, Fu-Jing; Zhou, Qing-Qing; Zhou, Ke; Du, Qing-Wei; Zhang, Dong; Xu, Shuang; Ding, Ji-Guang.

Afiliação

Hong L; Liang Hong, Qing-Feng Sun, Yang-He Wu, Hui Zhang, Rong-Quan Fu, Fu-Jing Cai, Qing-Qing Zhou, Ke Zhou, Qing-Wei Du, Dong Zhang, Shuang Xu, Ji-Guang Ding, Department of Infectious Diseases, the Third Affiliated Hospital to Wenzhou Medical University, Wenzhou 325200, Zhejiang Province, China.
Sun QF; Liang Hong, Qing-Feng Sun, Yang-He Wu, Hui Zhang, Rong-Quan Fu, Fu-Jing Cai, Qing-Qing Zhou, Ke Zhou, Qing-Wei Du, Dong Zhang, Shuang Xu, Ji-Guang Ding, Department of Infectious Diseases, the Third Affiliated Hospital to Wenzhou Medical University, Wenzhou 325200, Zhejiang Province, China.
Xu TY; Liang Hong, Qing-Feng Sun, Yang-He Wu, Hui Zhang, Rong-Quan Fu, Fu-Jing Cai, Qing-Qing Zhou, Ke Zhou, Qing-Wei Du, Dong Zhang, Shuang Xu, Ji-Guang Ding, Department of Infectious Diseases, the Third Affiliated Hospital to Wenzhou Medical University, Wenzhou 325200, Zhejiang Province, China.
Wu YH; Liang Hong, Qing-Feng Sun, Yang-He Wu, Hui Zhang, Rong-Quan Fu, Fu-Jing Cai, Qing-Qing Zhou, Ke Zhou, Qing-Wei Du, Dong Zhang, Shuang Xu, Ji-Guang Ding, Department of Infectious Diseases, the Third Affiliated Hospital to Wenzhou Medical University, Wenzhou 325200, Zhejiang Province, China.
Zhang H; Liang Hong, Qing-Feng Sun, Yang-He Wu, Hui Zhang, Rong-Quan Fu, Fu-Jing Cai, Qing-Qing Zhou, Ke Zhou, Qing-Wei Du, Dong Zhang, Shuang Xu, Ji-Guang Ding, Department of Infectious Diseases, the Third Affiliated Hospital to Wenzhou Medical University, Wenzhou 325200, Zhejiang Province, China.
Fu RQ; Liang Hong, Qing-Feng Sun, Yang-He Wu, Hui Zhang, Rong-Quan Fu, Fu-Jing Cai, Qing-Qing Zhou, Ke Zhou, Qing-Wei Du, Dong Zhang, Shuang Xu, Ji-Guang Ding, Department of Infectious Diseases, the Third Affiliated Hospital to Wenzhou Medical University, Wenzhou 325200, Zhejiang Province, China.
Cai FJ; Liang Hong, Qing-Feng Sun, Yang-He Wu, Hui Zhang, Rong-Quan Fu, Fu-Jing Cai, Qing-Qing Zhou, Ke Zhou, Qing-Wei Du, Dong Zhang, Shuang Xu, Ji-Guang Ding, Department of Infectious Diseases, the Third Affiliated Hospital to Wenzhou Medical University, Wenzhou 325200, Zhejiang Province, China.
Zhou QQ; Liang Hong, Qing-Feng Sun, Yang-He Wu, Hui Zhang, Rong-Quan Fu, Fu-Jing Cai, Qing-Qing Zhou, Ke Zhou, Qing-Wei Du, Dong Zhang, Shuang Xu, Ji-Guang Ding, Department of Infectious Diseases, the Third Affiliated Hospital to Wenzhou Medical University, Wenzhou 325200, Zhejiang Province, China.
Zhou K; Liang Hong, Qing-Feng Sun, Yang-He Wu, Hui Zhang, Rong-Quan Fu, Fu-Jing Cai, Qing-Qing Zhou, Ke Zhou, Qing-Wei Du, Dong Zhang, Shuang Xu, Ji-Guang Ding, Department of Infectious Diseases, the Third Affiliated Hospital to Wenzhou Medical University, Wenzhou 325200, Zhejiang Province, China.
Du QW; Liang Hong, Qing-Feng Sun, Yang-He Wu, Hui Zhang, Rong-Quan Fu, Fu-Jing Cai, Qing-Qing Zhou, Ke Zhou, Qing-Wei Du, Dong Zhang, Shuang Xu, Ji-Guang Ding, Department of Infectious Diseases, the Third Affiliated Hospital to Wenzhou Medical University, Wenzhou 325200, Zhejiang Province, China.
Zhang D; Liang Hong, Qing-Feng Sun, Yang-He Wu, Hui Zhang, Rong-Quan Fu, Fu-Jing Cai, Qing-Qing Zhou, Ke Zhou, Qing-Wei Du, Dong Zhang, Shuang Xu, Ji-Guang Ding, Department of Infectious Diseases, the Third Affiliated Hospital to Wenzhou Medical University, Wenzhou 325200, Zhejiang Province, China.
Xu S; Liang Hong, Qing-Feng Sun, Yang-He Wu, Hui Zhang, Rong-Quan Fu, Fu-Jing Cai, Qing-Qing Zhou, Ke Zhou, Qing-Wei Du, Dong Zhang, Shuang Xu, Ji-Guang Ding, Department of Infectious Diseases, the Third Affiliated Hospital to Wenzhou Medical University, Wenzhou 325200, Zhejiang Province, China.
Ding JG; Liang Hong, Qing-Feng Sun, Yang-He Wu, Hui Zhang, Rong-Quan Fu, Fu-Jing Cai, Qing-Qing Zhou, Ke Zhou, Qing-Wei Du, Dong Zhang, Shuang Xu, Ji-Guang Ding, Department of Infectious Diseases, the Third Affiliated Hospital to Wenzhou Medical University, Wenzhou 325200, Zhejiang Province, China.

World J Gastroenterol ; 22(9): 2779-88, 2016 Mar 07.

Article em En | MEDLINE | ID: mdl-26973416

Assuntos

Proteínas de Ciclo Celular/metabolismo; Células Estreladas do Fígado/metabolismo; Cirrose Hepática Experimental/metabolismo; Cirrose Hepática Experimental/prevenção & controle; Fígado/metabolismo; Proteínas Nucleares/metabolismo; Actinas/genética; Actinas/metabolismo; Animais; Tetracloreto de Carbono; Proteínas de Ciclo Celular/genética; Células Cultivadas; Colágeno Tipo I/genética; Colágeno Tipo I/metabolismo; Células Estreladas do Fígado/patologia; Fígado/patologia; Cirrose Hepática Experimental/induzido quimicamente; Cirrose Hepática Experimental/genética; Masculino; Camundongos Endogâmicos BALB C; Proteínas Nucleares/genética; Fosforilação; Interferência de RNA; RNA Interferente Pequeno/genética; RNA Interferente Pequeno/metabolismo; Espécies Reativas de Oxigênio/metabolismo; Transdução de Sinais; Proteína Smad3/metabolismo; Fatores de Tempo; Transfecção; Fator de Crescimento Transformador beta/metabolismo

Palavras-chave

Antioxidant; Gadd45a; Hepatic stellate cells; Hepatic ï¬brosis; Transforming growth factor-ß/Smad signaling

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Nucleares / Proteínas de Ciclo Celular / Células Estreladas do Fígado / Fígado / Cirrose Hepática Experimental Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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