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A SIRT2-Selective Inhibitor Promotes c-Myc Oncoprotein Degradation and Exhibits Broad Anticancer Activity.
Jing, Hui; Hu, Jing; He, Bin; Negrón Abril, Yashira L; Stupinski, Jack; Weiser, Keren; Carbonaro, Marisa; Chiang, Ying-Ling; Southard, Teresa; Giannakakou, Paraskevi; Weiss, Robert S; Lin, Hening.
Afiliação
  • Jing H; Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853, USA.
  • Hu J; Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853, USA.
  • He B; Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853, USA.
  • Negrón Abril YL; Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853, USA.
  • Stupinski J; Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853, USA.
  • Weiser K; Division of Hematology & Medical Oncology, Weill Medical College of Cornell University, 1300 York Avenue, C610C, New York, NY 10065-4896, USA.
  • Carbonaro M; Division of Hematology & Medical Oncology, Weill Medical College of Cornell University, 1300 York Avenue, C610C, New York, NY 10065-4896, USA.
  • Chiang YL; Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853, USA.
  • Southard T; Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853, USA.
  • Giannakakou P; Division of Hematology & Medical Oncology, Weill Medical College of Cornell University, 1300 York Avenue, C610C, New York, NY 10065-4896, USA.
  • Weiss RS; Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853, USA.
  • Lin H; Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853, USA; Howard Hughes Medical Institute, Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853, USA. Electronic address: hl379@cornell.edu.
Cancer Cell ; 29(3): 297-310, 2016 Mar 14.
Article em En | MEDLINE | ID: mdl-26977881
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas c-myc / Proteínas Oncogênicas / Sirtuína 2 / Proteólise / Antineoplásicos Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas c-myc / Proteínas Oncogênicas / Sirtuína 2 / Proteólise / Antineoplásicos Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article