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HDAC and PI3K Antagonists Cooperate to Inhibit Growth of MYC-Driven Medulloblastoma.
Pei, Yanxin; Liu, Kun-Wei; Wang, Jun; Garancher, Alexandra; Tao, Ran; Esparza, Lourdes A; Maier, Donna L; Udaka, Yoko T; Murad, Najiba; Morrissy, Sorana; Seker-Cin, Huriye; Brabetz, Sebastian; Qi, Lin; Kogiso, Mari; Schubert, Simone; Olson, James M; Cho, Yoon-Jae; Li, Xiao-Nan; Crawford, John R; Levy, Michael L; Kool, Marcel; Pfister, Stefan M; Taylor, Michael D; Wechsler-Reya, Robert J.
Afiliação
  • Pei Y; Tumor Initiation and Maintenance Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA; Cancer and Immunology Department, Brain Tumor Institute, Children's National Medical Center, Washington, DC 20010, USA.
  • Liu KW; Tumor Initiation and Maintenance Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.
  • Wang J; Tumor Initiation and Maintenance Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.
  • Garancher A; Tumor Initiation and Maintenance Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.
  • Tao R; Cancer and Immunology Department, Brain Tumor Institute, Children's National Medical Center, Washington, DC 20010, USA.
  • Esparza LA; Tumor Initiation and Maintenance Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.
  • Maier DL; Tumor Initiation and Maintenance Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.
  • Udaka YT; Department of Pediatrics, University of California San Diego - Rady Children's Hospital, San Diego, CA 92123, USA.
  • Murad N; Cancer and Immunology Department, Brain Tumor Institute, Children's National Medical Center, Washington, DC 20010, USA.
  • Morrissy S; Program in Developmental and Stem Cell Biology, Division of Neurosurgery, Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.
  • Seker-Cin H; Division of Pediatric Neuro-oncology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany; German Cancer Consortium, Core Center, 69120 Heidelberg, Germany.
  • Brabetz S; Division of Pediatric Neuro-oncology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany; German Cancer Consortium, Core Center, 69120 Heidelberg, Germany.
  • Qi L; Brain Tumor Program, Department of Pediatrics, Texas Children's Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.
  • Kogiso M; Brain Tumor Program, Department of Pediatrics, Texas Children's Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.
  • Schubert S; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA.
  • Olson JM; Fred Hutchinson Cancer Research Center, Seattle Children's Hospital, Seattle, WA 98109, USA.
  • Cho YJ; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA.
  • Li XN; Brain Tumor Program, Department of Pediatrics, Texas Children's Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.
  • Crawford JR; Department of Pediatrics, University of California San Diego - Rady Children's Hospital, San Diego, CA 92123, USA; Department of Neurosciences, University of California San Diego - Rady Children's Hospital, San Diego, CA 92123, USA.
  • Levy ML; Department of Neurosurgery, University of California San Diego - Rady Children's Hospital, San Diego, CA 92123, USA.
  • Kool M; Division of Pediatric Neuro-oncology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany; German Cancer Consortium, Core Center, 69120 Heidelberg, Germany.
  • Pfister SM; Division of Pediatric Neuro-oncology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany; German Cancer Consortium, Core Center, 69120 Heidelberg, Germany.
  • Taylor MD; Program in Developmental and Stem Cell Biology, Division of Neurosurgery, Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Division of Neurosurgery, Hospital for Sick Children, Toronto, ON M5G 1X8, Canada.
  • Wechsler-Reya RJ; Tumor Initiation and Maintenance Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA. Electronic address: rwreya@sbpdiscovery.org.
Cancer Cell ; 29(3): 311-323, 2016 Mar 14.
Article em En | MEDLINE | ID: mdl-26977882
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas c-myc / Proliferação de Células / Inibidores de Histona Desacetilases / Inibidores de Fosfoinositídeo-3 Quinase / Histona Desacetilases / Meduloblastoma Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas c-myc / Proliferação de Células / Inibidores de Histona Desacetilases / Inibidores de Fosfoinositídeo-3 Quinase / Histona Desacetilases / Meduloblastoma Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article