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Substrate engagement of integrins α5ß1 and αvß3 is necessary, but not sufficient, for high directional persistence in migration on fibronectin.
Missirlis, Dimitris; Haraszti, Tamás; Scheele, Catharina v C; Wiegand, Tina; Diaz, Carolina; Neubauer, Stefanie; Rechenmacher, Florian; Kessler, Horst; Spatz, Joachim P.
Afiliação
  • Missirlis D; Department of New Materials and Biosystems, Max Planck Institute for Intelligent Systems &University of Heidelberg, Department of Biophysical Chemistry Heisenbergstr. 3, D-70569 Stuttgart, Germany.
  • Haraszti T; Department of New Materials and Biosystems, Max Planck Institute for Intelligent Systems &University of Heidelberg, Department of Biophysical Chemistry Heisenbergstr. 3, D-70569 Stuttgart, Germany.
  • Scheele Cv; Department of New Materials and Biosystems, Max Planck Institute for Intelligent Systems &University of Heidelberg, Department of Biophysical Chemistry Heisenbergstr. 3, D-70569 Stuttgart, Germany.
  • Wiegand T; Department of New Materials and Biosystems, Max Planck Institute for Intelligent Systems &University of Heidelberg, Department of Biophysical Chemistry Heisenbergstr. 3, D-70569 Stuttgart, Germany.
  • Diaz C; Department of New Materials and Biosystems, Max Planck Institute for Intelligent Systems &University of Heidelberg, Department of Biophysical Chemistry Heisenbergstr. 3, D-70569 Stuttgart, Germany.
  • Neubauer S; Institute for Advanced Study (IAS) and Center of Integrated Protein Science (CIPSM), Department Chemie, Technische Universität München, Lichtenbergstr. 4, Garching, D-85747, Germany.
  • Rechenmacher F; Institute for Advanced Study (IAS) and Center of Integrated Protein Science (CIPSM), Department Chemie, Technische Universität München, Lichtenbergstr. 4, Garching, D-85747, Germany.
  • Kessler H; Institute for Advanced Study (IAS) and Center of Integrated Protein Science (CIPSM), Department Chemie, Technische Universität München, Lichtenbergstr. 4, Garching, D-85747, Germany.
  • Spatz JP; Department of New Materials and Biosystems, Max Planck Institute for Intelligent Systems &University of Heidelberg, Department of Biophysical Chemistry Heisenbergstr. 3, D-70569 Stuttgart, Germany.
Sci Rep ; 6: 23258, 2016 Mar 18.
Article em En | MEDLINE | ID: mdl-26987342
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fibronectinas / Integrina alfa5beta1 / Integrina alfaVbeta3 / Fibroblastos Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fibronectinas / Integrina alfa5beta1 / Integrina alfaVbeta3 / Fibroblastos Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article