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Estrogen and ERα enhanced ß-catenin degradation and suppressed its downstream target genes to block the metastatic function of HA22T hepatocellular carcinoma cells via modulating GSK-3ß and ß-TrCP expression.
Chen, Yu-Feng; Velmurugan, Bharath Kumar; Wang, Hwai-Lee; Tu, Chuan-Chou; Che, Ray-Jade; Chen, Ming-Cheng; Jen, Long-Bin; Vishwanadha, Vijaya Padma; Hsu, Hsi-Hsien; Huang, Chih-Yang.
Afiliação
  • Chen YF; Graduate Institute of Basic Medical Science, China Medical University, Taichung, Taiwan.
  • Velmurugan BK; Section of Cardiology, Yuan Rung Hospital, Yuanlin, Taiwan.
  • Wang HL; Graduate Institute of Basic Medical Science, China Medical University, Taichung, Taiwan.
  • Tu CC; Graduate Institute of Chinese Medical Science, China Medical University, Taichung, Taiwan.
  • Che RJ; Department of Internal Medicine, Division of Chest Medicine, Armed Force Taichung General Hospital, Taichung, Taiwan.
  • Chen MC; Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
  • Jen LB; Division of Colorectal Surgery, Veterans General Hospital, Taichung, Taiwan.
  • Vishwanadha VP; Department of Surgery, China Medical University Hospital, Taichung, Taiwan.
  • Hsu HH; Department of Biotechnology, Bharathiar University, Coimbatore, 641 046, India.
  • Huang CY; Division of Colorectal Surgery, Mackay Memorial Hospital, Taipei, Taiwan.
Environ Toxicol ; 32(2): 519-529, 2017 Feb.
Article em En | MEDLINE | ID: mdl-26990689
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Contendo Repetições de beta-Transducina / Receptor alfa de Estrogênio / Receptor beta de Estrogênio / Beta Catenina / Glicogênio Sintase Quinase 3 beta Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Contendo Repetições de beta-Transducina / Receptor alfa de Estrogênio / Receptor beta de Estrogênio / Beta Catenina / Glicogênio Sintase Quinase 3 beta Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article