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Co-operative and Hierarchical Binding of c-FLIP and Caspase-8: A Unified Model Defines How c-FLIP Isoforms Differentially Control Cell Fate.
Hughes, Michelle A; Powley, Ian R; Jukes-Jones, Rebekah; Horn, Sebastian; Feoktistova, Maria; Fairall, Louise; Schwabe, John W R; Leverkus, Martin; Cain, Kelvin; MacFarlane, Marion.
Afiliação
  • Hughes MA; MRC Toxicology Unit, Hodgkin Building, P.O. Box 138, Lancaster Road, Leicester LE1 9HN, UK.
  • Powley IR; MRC Toxicology Unit, Hodgkin Building, P.O. Box 138, Lancaster Road, Leicester LE1 9HN, UK.
  • Jukes-Jones R; MRC Toxicology Unit, Hodgkin Building, P.O. Box 138, Lancaster Road, Leicester LE1 9HN, UK.
  • Horn S; Department of Dermatology, Venereology and Allergology, Medical Faculty Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.
  • Feoktistova M; Department of Dermatology and Allergology, Medical Faculty of the RWTH Aachen, Pauwelsstraße 30, 52074 Aachen, Germany.
  • Fairall L; Henry Wellcome Laboratories of Structural Biology, Department of Molecular and Cell Biology, University of Leicester, Lancaster Road, Leicester LE1 9HN, UK.
  • Schwabe JW; Henry Wellcome Laboratories of Structural Biology, Department of Molecular and Cell Biology, University of Leicester, Lancaster Road, Leicester LE1 9HN, UK.
  • Leverkus M; Department of Dermatology and Allergology, Medical Faculty of the RWTH Aachen, Pauwelsstraße 30, 52074 Aachen, Germany.
  • Cain K; MRC Toxicology Unit, Hodgkin Building, P.O. Box 138, Lancaster Road, Leicester LE1 9HN, UK. Electronic address: kc5@le.ac.uk.
  • MacFarlane M; MRC Toxicology Unit, Hodgkin Building, P.O. Box 138, Lancaster Road, Leicester LE1 9HN, UK. Electronic address: mm21@le.ac.uk.
Mol Cell ; 61(6): 834-49, 2016 Mar 17.
Article em En | MEDLINE | ID: mdl-26990987

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linhagem da Célula / Isoformas de Proteínas / Caspase 8 / Proteína Reguladora de Apoptosis Semelhante a CASP8 e FADD Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linhagem da Célula / Isoformas de Proteínas / Caspase 8 / Proteína Reguladora de Apoptosis Semelhante a CASP8 e FADD Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article