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Computationally Designed Bispecific Antibodies using Negative State Repertoires.
Leaver-Fay, Andrew; Froning, Karen J; Atwell, Shane; Aldaz, Hector; Pustilnik, Anna; Lu, Frances; Huang, Flora; Yuan, Richard; Hassanali, Saleema; Chamberlain, Aaron K; Fitchett, Jonathan R; Demarest, Stephen J; Kuhlman, Brian.
Afiliação
  • Leaver-Fay A; Department of Biochemistry, University of North Carolina at Chapel Hill, 120 Mason Farm Road, Campus Box 7260, Chapel Hill, NC 27599, USA.
  • Froning KJ; Eli Lilly Biotechnology Center, 10300 Campus Point Drive, Suite 200, San Diego, CA 92121, USA.
  • Atwell S; Eli Lilly Biotechnology Center, 10300 Campus Point Drive, Suite 200, San Diego, CA 92121, USA.
  • Aldaz H; Eli Lilly Biotechnology Center, 10300 Campus Point Drive, Suite 200, San Diego, CA 92121, USA.
  • Pustilnik A; Eli Lilly Biotechnology Center, 10300 Campus Point Drive, Suite 200, San Diego, CA 92121, USA.
  • Lu F; Eli Lilly Biotechnology Center, 10300 Campus Point Drive, Suite 200, San Diego, CA 92121, USA.
  • Huang F; Eli Lilly Biotechnology Center, 10300 Campus Point Drive, Suite 200, San Diego, CA 92121, USA.
  • Yuan R; Eli Lilly Biotechnology Center, 10300 Campus Point Drive, Suite 200, San Diego, CA 92121, USA.
  • Hassanali S; Eli Lilly Biotechnology Center, 10300 Campus Point Drive, Suite 200, San Diego, CA 92121, USA.
  • Chamberlain AK; Eli Lilly Biotechnology Center, 10300 Campus Point Drive, Suite 200, San Diego, CA 92121, USA.
  • Fitchett JR; Eli Lilly Biotechnology Center, 10300 Campus Point Drive, Suite 200, San Diego, CA 92121, USA.
  • Demarest SJ; Eli Lilly Biotechnology Center, 10300 Campus Point Drive, Suite 200, San Diego, CA 92121, USA. Electronic address: demarestsj@lilly.com.
  • Kuhlman B; Department of Biochemistry, University of North Carolina at Chapel Hill, 120 Mason Farm Road, Campus Box 7260, Chapel Hill, NC 27599, USA; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, 101 Manning Drive, Chapel Hill, NC 27514, USA. Electronic address: bkuhlman@
Structure ; 24(4): 641-651, 2016 Apr 05.
Article em En | MEDLINE | ID: mdl-26996964
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imunoglobulina G / Fragmentos Fc das Imunoglobulinas / Engenharia de Proteínas / Cadeias Pesadas de Imunoglobulinas / Anticorpos Biespecíficos Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imunoglobulina G / Fragmentos Fc das Imunoglobulinas / Engenharia de Proteínas / Cadeias Pesadas de Imunoglobulinas / Anticorpos Biespecíficos Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2016 Tipo de documento: Article