Thiopurine S-methyltransferase testing for averting drug toxicity in patients receiving thiopurines: a systematic review.

Roy, Lilla M; Zur, Richard M; Uleryk, Elizabeth; Carew, Chris; Ito, Shinya; Ungar, Wendy J

Roy, Lilla M; Zur, Richard M; Uleryk, Elizabeth; Carew, Chris; Ito, Shinya; Ungar, Wendy J.

Afiliação

Roy LM; Child Health Evaluative Sciences, The Hospital for Sick Children Research Institute, Toronto, Canada.
Zur RM; Child Health Evaluative Sciences, The Hospital for Sick Children Research Institute, Toronto, Canada.
Uleryk E; Library Services, The Hospital for Sick Children, Toronto, Canada.
Carew C; Institute for Health Policy, Management & Evaluation, University of Toronto, Canada.
Ito S; Centre for Genetic Medicine, The Hospital for Sick Children, Toronto, Canada.
Ungar WJ; Division of Clinical Pharmacology & Toxicology, The Hospital for Sick Children, Toronto, Canada.

Pharmacogenomics ; 17(6): 633-56, 2016 04.

Article em En | MEDLINE | ID: mdl-27020704

Assuntos

Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos/genética; Metiltransferases/genética; Adolescente; Adulto; Feminino; Testes Genéticos/métodos; Genótipo; Humanos; Masculino; Mutação/genética; Fenótipo; Sensibilidade e Especificidade

Palavras-chave

QUADAS-2; enzyme deficiency; genetic test; phenotype; quality appraisal; sensitivity; specificity; systematic review; thiopurine S-methyltransferase

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos / Metiltransferases Tipo de estudo: Diagnostic_studies / Prognostic_studies / Systematic_reviews Limite: Adolescent / Adult / Female / Humans / Male Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google