Targeting melanoma with immunoliposomes coupled to anti-MAGE A1 TCR-like single-chain antibody.

Saeed, Mesha; van Brakel, Mandy; Zalba, Sara; Schooten, Erik; Rens, Joost A P; Koning, Gerben A; Debets, Reno; Ten Hagen, Timo L M

Saeed, Mesha; van Brakel, Mandy; Zalba, Sara; Schooten, Erik; Rens, Joost A P; Koning, Gerben A; Debets, Reno; Ten Hagen, Timo L M.

Afiliação

Saeed M; Laboratory of Experimental Surgical Oncology, Section Surgical Oncology, Department of Surgery, Erasmus MC, Rotterdam, the Netherlands.
van Brakel M; Laboratory of Tumor Immunology, Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
Zalba S; Laboratory of Experimental Surgical Oncology, Section Surgical Oncology, Department of Surgery, Erasmus MC, Rotterdam, the Netherlands.
Schooten E; Laboratory of Tumor Immunology, Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
Rens JA; Laboratory of Experimental Surgical Oncology, Section Surgical Oncology, Department of Surgery, Erasmus MC, Rotterdam, the Netherlands.
Koning GA; Laboratory of Experimental Surgical Oncology, Section Surgical Oncology, Department of Surgery, Erasmus MC, Rotterdam, the Netherlands.
Debets R; Laboratory of Tumor Immunology, Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
Ten Hagen TL; Laboratory of Experimental Surgical Oncology, Section Surgical Oncology, Department of Surgery, Erasmus MC, Rotterdam, the Netherlands.

Int J Nanomedicine ; 11: 955-75, 2016.

Article em En | MEDLINE | ID: mdl-27022262

Assuntos

Antígenos Específicos de Melanoma/imunologia; Melanoma/tratamento farmacológico; Melanoma/imunologia; Terapia de Alvo Molecular/métodos; Receptores de Antígenos de Linfócitos T/metabolismo; Anticorpos de Cadeia Única/administração & dosagem; Anticorpos de Cadeia Única/imunologia; Linfócitos B/imunologia; Linfócitos B/metabolismo; Linhagem Celular Tumoral; Antígeno HLA-A1/metabolismo; Humanos; Lipossomos; Melanoma/metabolismo; Anticorpos de Cadeia Única/uso terapêutico; Linfócitos T/imunologia; Linfócitos T/metabolismo

Palavras-chave

HLA-A1 targeting; cancer; cancer testis antigens; immunotherapy; nanoparticles

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de Antígenos de Linfócitos T / Anticorpos de Cadeia Única / Antígenos Específicos de Melanoma / Terapia de Alvo Molecular / Melanoma Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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