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The association of aberrant folylpolyglutamate synthetase splicing with ex vivo methotrexate resistance and clinical outcome in childhood acute lymphoblastic leukemia.
Wojtuszkiewicz, Anna; Assaraf, Yehuda G; Hoekstra, Mirthe; Sciarrillo, Rocco; Jansen, Gerrit; Peters, Godefridus J; Pieters, Rob; Sonneveld, Edwin; Escherich, Gabriele; Kaspers, Gertjan J L; Cloos, Jacqueline.
Afiliação
  • Wojtuszkiewicz A; Dept of Pediatric Oncology/Hematology, VU University Medical Center, Amsterdam, The Netherlands Dept. of Hematology, VU University Medical Center, Amsterdam, The Netherlands.
  • Assaraf YG; Dept. of Biology, Technion-Israel Institute of Technology, Haifa, Israel.
  • Hoekstra M; Dept of Pediatric Oncology/Hematology, VU University Medical Center, Amsterdam, The Netherlands.
  • Sciarrillo R; Dept of Pediatric Oncology/Hematology, VU University Medical Center, Amsterdam, The Netherlands Dept. of Hematology, VU University Medical Center, Amsterdam, The Netherlands Dept. of Medical Oncology, VU University Medical Center, Amsterdam, The Netherlands.
  • Jansen G; Dept. of Rheumatology, VU University Medical Center, Amsterdam, The Netherlands.
  • Peters GJ; Dept. of Medical Oncology, VU University Medical Center, Amsterdam, The Netherlands.
  • Pieters R; Dutch Childhood Oncology Group (DCOG), The Hague, The Netherlands Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
  • Sonneveld E; Dutch Childhood Oncology Group (DCOG), The Hague, The Netherlands.
  • Escherich G; Clinic of Pediatric Hematology/Oncology, University Medical Center Eppendorf, Hamburg, Germany.
  • Kaspers GJ; Dept of Pediatric Oncology/Hematology, VU University Medical Center, Amsterdam, The Netherlands.
  • Cloos J; Dept of Pediatric Oncology/Hematology, VU University Medical Center, Amsterdam, The Netherlands Dept. of Hematology, VU University Medical Center, Amsterdam, The Netherlands j.cloos@vumc.nl.
Haematologica ; 101(7): e291-4, 2016 07.
Article em En | MEDLINE | ID: mdl-27036162
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeo Sintases / Splicing de RNA / Metotrexato / Resistencia a Medicamentos Antineoplásicos / Leucemia-Linfoma Linfoblástico de Células Precursoras / Proteínas de Neoplasias Tipo de estudo: Risk_factors_studies Limite: Adolescent / Child / Child, preschool / Female / Humans / Male Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeo Sintases / Splicing de RNA / Metotrexato / Resistencia a Medicamentos Antineoplásicos / Leucemia-Linfoma Linfoblástico de Células Precursoras / Proteínas de Neoplasias Tipo de estudo: Risk_factors_studies Limite: Adolescent / Child / Child, preschool / Female / Humans / Male Idioma: En Ano de publicação: 2016 Tipo de documento: Article