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Type 2 diabetes mellitus induces congenital heart defects in murine embryos by increasing oxidative stress, endoplasmic reticulum stress, and apoptosis.
Wu, Yanqing; Reece, E Albert; Zhong, Jianxiang; Dong, Daoyin; Shen, Wei-Bin; Harman, Christopher R; Yang, Peixin.
Afiliação
  • Wu Y; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD.
  • Reece EA; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD.
  • Zhong J; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD.
  • Dong D; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD.
  • Shen WB; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD.
  • Harman CR; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD.
  • Yang P; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD. Electronic address: pyang@fpi.umaryland.edu.
Am J Obstet Gynecol ; 215(3): 366.e1-366.e10, 2016 09.
Article em En | MEDLINE | ID: mdl-27038779
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diabetes Gestacional / Apoptose / Estresse Oxidativo / Estresse do Retículo Endoplasmático / Cardiopatias Congênitas Tipo de estudo: Prognostic_studies Limite: Animals / Pregnancy Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diabetes Gestacional / Apoptose / Estresse Oxidativo / Estresse do Retículo Endoplasmático / Cardiopatias Congênitas Tipo de estudo: Prognostic_studies Limite: Animals / Pregnancy Idioma: En Ano de publicação: 2016 Tipo de documento: Article