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Systemic TAK-242 prevents intrathecal LPS evoked hyperalgesia in male, but not female mice and prevents delayed allodynia following intraplantar formalin in both male and female mice: The role of TLR4 in the evolution of a persistent pain state.
Woller, Sarah A; Ravula, Satheesh B; Tucci, Fabio C; Beaton, Graham; Corr, Maripat; Isseroff, R Rivkah; Soulika, Athena M; Chigbrow, Marianne; Eddinger, Kelly A; Yaksh, Tony L.
Afiliação
  • Woller SA; Department of Anesthesiology, University of California San Diego, La Jolla, CA, USA; Department of Medicine, Division of Rheumatology, Allergy, and Immunology, University of California San Diego, La Jolla, CA, USA. Electronic address: swoller@ucsd.edu.
  • Ravula SB; Epigen Biosciences Inc., 10225 Barnes Canyon Road, Suite A104, San Diego, CA 92121, USA. Electronic address: sravula@epigenbiosciences.com.
  • Tucci FC; Epigen Biosciences Inc., 10225 Barnes Canyon Road, Suite A104, San Diego, CA 92121, USA. Electronic address: ftucci@epigenbiosciences.com.
  • Beaton G; Epigen Biosciences Inc., 10225 Barnes Canyon Road, Suite A104, San Diego, CA 92121, USA. Electronic address: gbeaton@epigenbiosciences.com.
  • Corr M; Department of Medicine, Division of Rheumatology, Allergy, and Immunology, University of California San Diego, La Jolla, CA, USA. Electronic address: mpcorr@ucsd.edu.
  • Isseroff RR; Department of Dermatology, School of Medicine, University of California, Davis, CA, USA. Electronic address: rrisseroff@ucdavis.edu.
  • Soulika AM; Department of Dermatology, School of Medicine, University of California, Davis, CA, USA; Shriners Hospital for Children, Northern California, Sacramento, CA, USA. Electronic address: asoulika@ucdavis.edu.
  • Chigbrow M; Department of Dermatology, School of Medicine, University of California, Davis, CA, USA. Electronic address: mchigbrow@ucdavis.edu.
  • Eddinger KA; Department of Anesthesiology, University of California San Diego, La Jolla, CA, USA. Electronic address: keddinger@ucsd.edu.
  • Yaksh TL; Department of Anesthesiology, University of California San Diego, La Jolla, CA, USA. Electronic address: tyaksh@ucsd.edu.
Brain Behav Immun ; 56: 271-80, 2016 08.
Article em En | MEDLINE | ID: mdl-27044335
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfonamidas / Transdução de Sinais / Fator de Necrose Tumoral alfa / Receptor 4 Toll-Like / Dor Crônica / Hiperalgesia Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfonamidas / Transdução de Sinais / Fator de Necrose Tumoral alfa / Receptor 4 Toll-Like / Dor Crônica / Hiperalgesia Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article