Emtricitabine is a substrate of MATE1 but not of OCT1, OCT2, P-gp, BCRP or MRP2 transporters.

Reznicek, Josef; Ceckova, Martina; Cerveny, Lukas; Müller, Fabian; Staud, Frantisek

Reznicek, Josef; Ceckova, Martina; Cerveny, Lukas; Müller, Fabian; Staud, Frantisek.

Afiliação

Reznicek J; a Department of Pharmacology and Toxicology , Faculty of Pharmacy, Charles University in Prague , Hradec Kralove , Czech Republic and.
Ceckova M; a Department of Pharmacology and Toxicology , Faculty of Pharmacy, Charles University in Prague , Hradec Kralove , Czech Republic and.
Cerveny L; a Department of Pharmacology and Toxicology , Faculty of Pharmacy, Charles University in Prague , Hradec Kralove , Czech Republic and.
Müller F; b Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-Universität Erlangen-Nürnberg , Erlangen , Germany.
Staud F; a Department of Pharmacology and Toxicology , Faculty of Pharmacy, Charles University in Prague , Hradec Kralove , Czech Republic and.

Xenobiotica ; 47(1): 77-85, 2017 Jan.

Article em En | MEDLINE | ID: mdl-27052107

Assuntos

Emtricitabina/metabolismo; Proteínas de Transporte de Cátions Orgânicos/metabolismo; Inibidores da Transcriptase Reversa/metabolismo; Membro 1 da Subfamília B de Cassetes de Ligação de ATP/metabolismo; Animais; Cães; Células Madin Darby de Rim Canino

Palavras-chave

Cimetidine; MDCK cells; combination antiretroviral therapy; drugdrug interactions; pharmacokinetics; ritonavir

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores da Transcriptase Reversa / Proteínas de Transporte de Cátions Orgânicos / Emtricitabina Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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