Characterization of skin Port-Wine Stain and Hemangioma vascular lesions using Doppler OCT.
Skin Res Technol
; 22(2): 223-9, 2016 May.
Article
em En
| MEDLINE
| ID: mdl-27060596
ABSTRACT
BACKGROUND:
Port-Wine Stains (PWS) are vascular malformations of the dermis, whereas hemangiomas are vascular tumors usually present at birth. Early non-invasive diagnosis of the vascular lesion would greatly increase treatment efficiency. We propose to use optical coherence tomography (OCT), a morphological imaging technique, coupled with functional blood-flow Doppler modality.METHODS:
We imaged lesions from five patients one with PWS, four with hemangiomas, using a Thorlabs Swept-Source OCT system at 1325 nm. Additional Doppler images allow for distinguishing blood vessels from empty cavities that appear similar on conventional OCT images.RESULTS:
We are able to distinguish between normal skin and vascular lesions. The PWS lesion presents blood vessels of mean diameter 114 µm with a standard deviation of 92 µm, and mean depth 304 µm with a standard deviation of 99 µm. The hemangiomas present blood vessels of mean diameter 39 µm with a standard deviation of 19 µm, and mean depth 298 µm with a standard deviation of 133 µm.CONCLUSION:
We show a significant difference between the vascular characteristics of the studied PWS and hemangiomas lesions. We believe that OCT complemented by Doppler OCT could be a promising method for future non-invasive diagnosis and monitoring of some vascular lesions.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pele
/
Hemangioma Capilar
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Ultrassonografia Doppler
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Mancha Vinho do Porto
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Tomografia de Coerência Óptica
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Imagem Multimodal
Tipo de estudo:
Diagnostic_studies
/
Evaluation_studies
Limite:
Child
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Child, preschool
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article