Inhibition of Growth by Combined Treatment with Inhibitors of Lactate Dehydrogenase and either Phenformin or Inhibitors of 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase 3.

Lea, Michael A; Guzman, Yolanda; Desbordes, Charles

Lea, Michael A; Guzman, Yolanda; Desbordes, Charles.

Afiliação

Lea MA; Department of Microbiology, Biochemistry and Molecular Genetics, Rutgers New Jersey Medical School, Newark, NJ, U.S.A. lea@njms.rutgers.edu.
Guzman Y; Department of Microbiology, Biochemistry and Molecular Genetics, Rutgers New Jersey Medical School, Newark, NJ, U.S.A.
Desbordes C; Department of Microbiology, Biochemistry and Molecular Genetics, Rutgers New Jersey Medical School, Newark, NJ, U.S.A. Department of Biology, Medgar Evers College - City University of New York, Brooklyn, NY, U.S.A.

Anticancer Res ; 36(4): 1479-88, 2016 Apr.

Article em En | MEDLINE | ID: mdl-27069123

Assuntos

Antineoplásicos/farmacologia; Hipoglicemiantes/farmacologia; L-Lactato Desidrogenase/antagonistas & inibidores; Fenformin/farmacologia; Fosfofrutoquinase-2/antagonistas & inibidores; Piridinas/farmacologia; Linhagem Celular Tumoral; Proliferação de Células/efeitos dos fármacos; Glucose/metabolismo; Humanos

Palavras-chave

Bladder cancer; PFKFB3 inhibitor; colon; glycolysis; growth; lactate dehydrogenase; phenformin

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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenformin / Piridinas / Fosfofrutoquinase-2 / Hipoglicemiantes / L-Lactato Desidrogenase / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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