Among a panel of polymorphisms in genes related to oxidative stress, CAT-262 C>T, GPX1 Pro198Leu and GSTP1 Ile105Val influence the risk of developing BCR-ABL negative myeloproliferative neoplasms.

Trifa, Adrian P; Banescu, Claudia; Dima, Delia; Bojan, Anca S; Tevet, Mihaela; Moldovan, Valeriu G; Vesa, Ètefan C; Murat, Meilin; Pop, Ioan V; Skrypnyk, Cristina; Popp, Radu A

Trifa, Adrian P; Banescu, Claudia; Dima, Delia; Bojan, Anca S; Tevet, Mihaela; Moldovan, Valeriu G; Vesa, Ètefan C; Murat, Meilin; Pop, Ioan V; Skrypnyk, Cristina; Popp, Radu A.

Afiliação

Trifa AP; a Department of Medical Genetics, "Iuliu HaÈieganu" University of Medicine and Pharmacy , Cluj-Napoca , Romania.
Banescu C; b Department of Genetics , "Ion ChiricuÈa" Cancer Institute , Cluj-Napoca , Romania.
Dima D; c Department of Genetics , University of Medicine and Pharmacy , Tîrgu-MureÈ , Romania.
Bojan AS; d Department of Hematology, "Ion ChiricuÈa" Cancer Institute , Cluj-Napoca , Romania.
Tevet M; d Department of Hematology, "Ion ChiricuÈa" Cancer Institute , Cluj-Napoca , Romania.
Moldovan VG; e Department of Hematology, "Iuliu HaÈieganu" University of Medicine and Pharmacy , Cluj-Napoca , Romania.
Vesa ÈC; f Department of Hematology , Colentina Hospital , Bucharest , Romania.
Murat M; c Department of Genetics , University of Medicine and Pharmacy , Tîrgu-MureÈ , Romania.
Pop IV; g Department of Pharmacology and Toxicology, "Iuliu HaÈieganu" University of Medicine and Pharmacy , Cluj-Napoca , Romania.
Skrypnyk C; f Department of Hematology , Colentina Hospital , Bucharest , Romania.
Popp RA; a Department of Medical Genetics, "Iuliu HaÈieganu" University of Medicine and Pharmacy , Cluj-Napoca , Romania.

Hematology ; 21(9): 520-5, 2016 Oct.

Article em En | MEDLINE | ID: mdl-27077777

Assuntos

Proteínas de Fusão bcr-abl/genética; Transtornos Mieloproliferativos/genética; Estresse Oxidativo/genética; Adulto; Idoso; Idoso de 80 Anos ou mais; Catalase/genética; Feminino; Genes abl; Genótipo; Glutationa Peroxidase/genética; Glutationa S-Transferase pi/genética; Glutationa Transferase/genética; Humanos; Masculino; Pessoa de Meia-Idade; Transtornos Mieloproliferativos/enzimologia; Transtornos Mieloproliferativos/metabolismo; Polimorfismo de Nucleotídeo Único; Superóxido Dismutase/genética; Glutationa Peroxidase GPX1

Palavras-chave

BCR-ABL negative myeloproliferative neoplasms; Genetic polymorphisms; Oxidative stress

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Fusão bcr-abl / Estresse Oxidativo / Transtornos Mieloproliferativos Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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