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A sustained release formulation of novel quininib-hyaluronan microneedles inhibits angiogenesis and retinal vascular permeability in vivo.
Galvin, Orla; Srivastava, Akshay; Carroll, Oliver; Kulkarni, Rajiv; Dykes, Steve; Vickers, Steven; Dickinson, Keith; Reynolds, Alison L; Kilty, Claire; Redmond, Gareth; Jones, Rob; Cheetham, Sharon; Pandit, Abhay; Kennedy, Breandán N.
Afiliação
  • Galvin O; UCD School of Biomolecular & Biomedical Science, UCD Conway Institute, University College Dublin, Dublin 4, Ireland.
  • Srivastava A; Centre for Research in Medical Devices (CÚRAM), National University of Ireland Galway, Galway, Ireland.
  • Carroll O; Centre for Research in Medical Devices (CÚRAM), National University of Ireland Galway, Galway, Ireland.
  • Kulkarni R; RenaSci Ltd, BioCity, Pennyfoot Street, Nottingham NG1 1GF, UK.
  • Dykes S; RenaSci Ltd, BioCity, Pennyfoot Street, Nottingham NG1 1GF, UK.
  • Vickers S; RenaSci Ltd, BioCity, Pennyfoot Street, Nottingham NG1 1GF, UK.
  • Dickinson K; RenaSci Ltd, BioCity, Pennyfoot Street, Nottingham NG1 1GF, UK.
  • Reynolds AL; UCD School of Biomolecular & Biomedical Science, UCD Conway Institute, University College Dublin, Dublin 4, Ireland.
  • Kilty C; UCD School of Biomolecular & Biomedical Science, UCD Conway Institute, University College Dublin, Dublin 4, Ireland.
  • Redmond G; UCD School of Chemistry, University College Dublin, Dublin 4, Ireland.
  • Jones R; RenaSci Ltd, BioCity, Pennyfoot Street, Nottingham NG1 1GF, UK.
  • Cheetham S; RenaSci Ltd, BioCity, Pennyfoot Street, Nottingham NG1 1GF, UK.
  • Pandit A; Centre for Research in Medical Devices (CÚRAM), National University of Ireland Galway, Galway, Ireland.
  • Kennedy BN; UCD School of Biomolecular & Biomedical Science, UCD Conway Institute, University College Dublin, Dublin 4, Ireland. Electronic address: brendan.kennedy@ucd.ie.
J Control Release ; 233: 198-207, 2016 07 10.
Article em En | MEDLINE | ID: mdl-27086168
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenóis / Quinolinas / Neovascularização Retiniana / Sistemas de Liberação de Medicamentos / Inibidores da Angiogênese / Ácido Hialurônico Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenóis / Quinolinas / Neovascularização Retiniana / Sistemas de Liberação de Medicamentos / Inibidores da Angiogênese / Ácido Hialurônico Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article