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Quantitative assessment of BRAF V600 mutant circulating cell-free tumor DNA as a tool for therapeutic monitoring in metastatic melanoma patients treated with BRAF/MEK inhibitors.
Schreuer, Max; Meersseman, Geert; Van Den Herrewegen, Sari; Jansen, Yanina; Chevolet, Ines; Bott, Ambre; Wilgenhof, Sofie; Seremet, Teofila; Jacobs, Bart; Buyl, Ronald; Maertens, Geert; Neyns, Bart.
Afiliação
  • Schreuer M; Department of Medical Oncology, Universitair Ziekenhuis Brussel (UZ Brussel), Vrije Universiteit Brussel (VUB), Laarbeeklaan 101, 1090, Brussels, Belgium. max.schreuer@uzbrussel.be.
  • Meersseman G; Biocartis, Generaal De Wittelaan 11 B3, 2800, Mechelen, Belgium.
  • Van Den Herrewegen S; Biocartis, Generaal De Wittelaan 11 B3, 2800, Mechelen, Belgium.
  • Jansen Y; Department of Medical Oncology, Universitair Ziekenhuis Brussel (UZ Brussel), Vrije Universiteit Brussel (VUB), Laarbeeklaan 101, 1090, Brussels, Belgium.
  • Chevolet I; Department of Dermatology, Universitair ziekenhuis Gent (UZ Gent), Universiteit Gent (UGent), De Pintelaan 185, 9000, Ghent, Belgium.
  • Bott A; Department of Medical Oncology, Universitair Ziekenhuis Brussel (UZ Brussel), Vrije Universiteit Brussel (VUB), Laarbeeklaan 101, 1090, Brussels, Belgium.
  • Wilgenhof S; Department of Medical Oncology, Universitair Ziekenhuis Brussel (UZ Brussel), Vrije Universiteit Brussel (VUB), Laarbeeklaan 101, 1090, Brussels, Belgium.
  • Seremet T; Department of Medical Oncology, Universitair Ziekenhuis Brussel (UZ Brussel), Vrije Universiteit Brussel (VUB), Laarbeeklaan 101, 1090, Brussels, Belgium.
  • Jacobs B; Biocartis, Generaal De Wittelaan 11 B3, 2800, Mechelen, Belgium.
  • Buyl R; Department of Biostatistics and Medical Informatics, Vrije Universiteit Brussel (VUB), Laarbeeklaan, 103, 1090, Brussels, Belgium.
  • Maertens G; Biocartis, Generaal De Wittelaan 11 B3, 2800, Mechelen, Belgium.
  • Neyns B; Department of Medical Oncology, Universitair Ziekenhuis Brussel (UZ Brussel), Vrije Universiteit Brussel (VUB), Laarbeeklaan 101, 1090, Brussels, Belgium.
J Transl Med ; 14: 95, 2016 Apr 19.
Article em En | MEDLINE | ID: mdl-27095081
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA de Neoplasias / Monitoramento de Medicamentos / Proteínas Proto-Oncogênicas B-raf / Inibidores de Proteínas Quinases / Melanoma / Mutação / Células Neoplásicas Circulantes Limite: Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2016 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA de Neoplasias / Monitoramento de Medicamentos / Proteínas Proto-Oncogênicas B-raf / Inibidores de Proteínas Quinases / Melanoma / Mutação / Células Neoplásicas Circulantes Limite: Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2016 Tipo de documento: Article