Parkinson's disease-like forelimb akinesia induced by BmK I, a sodium channel modulator.

Zhu, Hongyan; Wang, Ziyi; Jin, Jiahui; Pei, Xiao; Zhao, Yuxiao; Wu, Hao; Lin, Weide; Tao, Jie; Ji, Yonghua

Zhu, Hongyan; Wang, Ziyi; Jin, Jiahui; Pei, Xiao; Zhao, Yuxiao; Wu, Hao; Lin, Weide; Tao, Jie; Ji, Yonghua.

Afiliação

Zhu H; Laboratory of Neuropharmacology and Neurotoxicology, School of Life Science, Shanghai University, Shanghai, China. Electronic address: zhyred@shu.edu.cn.
Wang Z; Laboratory of Neuropharmacology and Neurotoxicology, School of Life Science, Shanghai University, Shanghai, China. Electronic address: yhji@shu.edu.cn.
Jin J; Laboratory of Neuropharmacology and Neurotoxicology, School of Life Science, Shanghai University, Shanghai, China.
Pei X; Laboratory of Neuropharmacology and Neurotoxicology, School of Life Science, Shanghai University, Shanghai, China.
Zhao Y; Laboratory of Neuropharmacology and Neurotoxicology, School of Life Science, Shanghai University, Shanghai, China.
Wu H; Laboratory of Neuropharmacology and Neurotoxicology, School of Life Science, Shanghai University, Shanghai, China.
Lin W; Laboratory of Neuropharmacology and Neurotoxicology, School of Life Science, Shanghai University, Shanghai, China.
Tao J; Laboratory of Neuropharmacology and Neurotoxicology, School of Life Science, Shanghai University, Shanghai, China.
Ji Y; Laboratory of Neuropharmacology and Neurotoxicology, School of Life Science, Shanghai University, Shanghai, China.

Behav Brain Res ; 308: 166-76, 2016 07 15.

Article em En | MEDLINE | ID: mdl-27108049

Assuntos

Membro Anterior/fisiopatologia; Moduladores de Transporte de Membrana/farmacologia; Venenos de Escorpião/farmacologia; Animais; Diferenciação Celular/efeitos dos fármacos; Linhagem Celular Tumoral; Modelos Animais de Doenças; Comportamento Exploratório/efeitos dos fármacos; Membro Anterior/efeitos dos fármacos; Globo Pálido/efeitos dos fármacos; Globo Pálido/fisiologia; Glutamato Descarboxilase/metabolismo; Humanos; Masculino; Potenciais da Membrana/efeitos dos fármacos; Neuroblastoma/patologia; Oxidopamina/farmacologia; Doença de Parkinson/etiologia; Ratos; Ratos Sprague-Dawley; Canais de Sódio/metabolismo; Tirosina 3-Mono-Oxigenase/metabolismo

Palavras-chave

Forelimb akinesia; Parkinson disease; Voltage-gated Na(+) channels; α-Like scorpion toxin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Venenos de Escorpião / Moduladores de Transporte de Membrana / Membro Anterior Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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