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Secretory pathway retention of mutant prion protein induces p38-MAPK activation and lethal disease in mice.
Puig, Berta; Altmeppen, Hermann C; Ulbrich, Sarah; Linsenmeier, Luise; Krasemann, Susanne; Chakroun, Karima; Acevedo-Morantes, Claudia Y; Wille, Holger; Tatzelt, Jörg; Glatzel, Markus.
Afiliação
  • Puig B; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.
  • Altmeppen HC; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.
  • Ulbrich S; Department of Biochemistry of Neurodegenerative Diseases, Institute of Biochemistry und Pathobiochemistry, Ruhr University Bochum, Bochum 44801, Germany.
  • Linsenmeier L; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.
  • Krasemann S; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.
  • Chakroun K; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.
  • Acevedo-Morantes CY; Centre for Prions and Protein Folding Diseases and Department of Biochemistry, University of Alberta, Edmonton, T6G 2M8 Alberta, Canada.
  • Wille H; Centre for Prions and Protein Folding Diseases and Department of Biochemistry, University of Alberta, Edmonton, T6G 2M8 Alberta, Canada.
  • Tatzelt J; Department of Biochemistry of Neurodegenerative Diseases, Institute of Biochemistry und Pathobiochemistry, Ruhr University Bochum, Bochum 44801, Germany.
  • Glatzel M; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.
Sci Rep ; 6: 24970, 2016 04 27.
Article em En | MEDLINE | ID: mdl-27117504
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Priônicas / Proteínas Quinases p38 Ativadas por Mitógeno / Via Secretória / Proteínas Priônicas Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Priônicas / Proteínas Quinases p38 Ativadas por Mitógeno / Via Secretória / Proteínas Priônicas Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article