The Amplifying Pathway of the ß-Cell Contributes to Diet-induced Obesity.

Vetterli, Laurène; Carobbio, Stefania; Frigerio, Francesca; Karaca, Melis; Maechler, Pierre

Vetterli, Laurène; Carobbio, Stefania; Frigerio, Francesca; Karaca, Melis; Maechler, Pierre.

Afiliação

Vetterli L; From the Department of Cell Physiology and Metabolism and Faculty Diabetes Center, Geneva University Medical Centre, 1211 Geneva 4, Switzerland.
Carobbio S; From the Department of Cell Physiology and Metabolism and Faculty Diabetes Center, Geneva University Medical Centre, 1211 Geneva 4, Switzerland.
Frigerio F; From the Department of Cell Physiology and Metabolism and Faculty Diabetes Center, Geneva University Medical Centre, 1211 Geneva 4, Switzerland.
Karaca M; From the Department of Cell Physiology and Metabolism and Faculty Diabetes Center, Geneva University Medical Centre, 1211 Geneva 4, Switzerland.
Maechler P; From the Department of Cell Physiology and Metabolism and Faculty Diabetes Center, Geneva University Medical Centre, 1211 Geneva 4, Switzerland Pierre.Maechler@unige.ch.

J Biol Chem ; 291(25): 13063-75, 2016 Jun 17.

Article em En | MEDLINE | ID: mdl-27137930

Assuntos

Dieta Hiperlipídica/efeitos adversos; Células Secretoras de Insulina/fisiologia; Obesidade/etiologia; Transdução de Sinais; Animais; Metabolismo Basal; Células Cultivadas; Intolerância à Glucose; Glutamato Desidrogenase/genética; Metabolismo dos Lipídeos; Masculino; Camundongos da Linhagem 129; Camundongos Endogâmicos C57BL; Camundongos Knockout; Obesidade/patologia

Palavras-chave

beta cell (B-cell); insulin secretion; obesity; transgenic mice; type 2 diabetes

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Células Secretoras de Insulina / Dieta Hiperlipídica / Obesidade Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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